B. Tech Biosciences and Bioengineering

BT 304 Immunology 3-0-0-6

Syllabus: Properties and overview of immune responses cells and tissue of the immune system, leukocyte migration into tissues, antibodies and antigen. Innate Immunity: major histocompatability complex. Antigen processing and presentation to T lymphocyte. Antigen receptors gene rearrangement and lymphocyte development, Immune receptors and signal transduction, activation of T lymphocytes. Adaptive immunity: effector mechanisms, B cell activation and antibody production, regional immunity, Immune memory response. Immunologic tolerance: autoimmunity, immunity to Microbes, transplantation immunology, tumor Immunology. Hypersensitivity: IgE dependent immune response, allergic disease, congenital and acquired immune deficiencies.

Texts:

1. A. Abbas, A. H. Lichtman and S. Pillai, Cellular and Molecular Immunology, 7^th Updated Edition, Saunders, 2011.

2. R. Tizard, Veterinary Immunology, 7^th Edition, Saunders, 2004.

3. J. Kuby, Kuby Immunology, 4^th Edition, W. H. Freeman & Co. Ltd., 2000.

4. L. M. Sompayrac, How the Immune System Works, 5^th Edition, Blackwell Science, 2015.

5. W. L. Anderson, Immnology, 1^st Edition, Wiley-Blackwell, 1999.

6. C. A. Janeway, Jr and P. Travers, Immunobiology - The Immune System in Health and Disease, 5^th Edition, Garland Science Publishing, 2001.

7. M. Roitt, J. Brostoff and D. K. Male, Immunology, 6^th Edition, Mosby, 2001.

8. A. Abbas and A. H. Lichtman, Basic Immunology, 1^st Edition, Saunders, 2001.

References:

1. D. M. Weir and J. Stewart, Immunology, Churchill Livingstone, 1997.

2. M. O. Cooke, J. Trowsdale, B. Champion and D. K. Male, Advanced Immunology, Mosby, 1996.

3. R. Coico, G. Sunshine and E. Benjammini, Immunology: A Short Course, Wiley-Liss, 2003.