B. Tech Biosciences and Bioengineering

BT 308        Bioengineering        3-0-0-6

Syllabus: Introduction; General configuration of biosensor; Types of biosensors; Basic principle and instrumentation of different types of biosensors: electrochemical, optical, piezoelectric, magnetic and calorimetric biosensors; Advance materials and techniques for developing biosensors, diagnostics and therapeutics; Recent advances in bio-based sensors and diagnostics. Introduction; Principles of regenerative medicine; Tissue engineering approaches, its need and current available technologies; Biomaterials in tissue engineering, biomaterial properties, biodegradability and compatibility; 3D scaffold processing techniques; Stem cells, primary cells and cell lines, their culturing and differentiation; Cell-material interactions; Bioreactors in tissue regeneration; 3D in vitro disease models; Drug delivery, drug delivery formats; Recent applications in regenerative medicine.

Texts:

1. L. Gorton, Biosensors and Modern Bio-Specific Analytical Techniques, Volume XLIV, Elsevier, 2005.

2. B. D. Malhotra and A. P. F. Turner, Advances in Biosensors, Volume V, Elsevier Science, 2003.

3. R. Lanza, R. Langer and J. P. Vacanti, The Principles of Tissue Engineering, 4^th Edition, Academic Press, 2013.

4. R. Lanza and A. Atala, Essentials of Stem Cell Biology, 3^rd Edition, Academic Press, 2013.

5. B. D. Ratner, A. S. Hoffman, F. J. Schoen and J. E. Lemons, Biomaterials Science: An Introduction to Materials and Medicine, 3^rd Edition, Academic Press, 2012.

6. R. I. Freshney, Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, 6^th Edition, Wiley-Blackwell, 2010.

References:

1. J. B. Park and J. D. Bronzino, Biomaterials: Principles and Applications, CRC Press, 2002.

2. K. C. Dee, D. A. Puleo and R. Bizios, An Introduction to Tissue-Biomaterial Interactions, Wiley, 2002.