Single crystal Xray Diffractometer

Description:
BRUKER D8 VENTURE SC-XRD system is equipped with dual X-ray sources (Mo and Cu), Photon II detector, APEX3 and SHEXLTL softwares. For greater flexibility, this system allows the combination of Mo and Cu X-ray sources and a highly accurate and multi-axis goniometer with optical encoders. The detector supporting shutter-less data collection delivers excellent spatial accuracy, exceptional sensitivity and high quantum efficiency. The detector is optimized for both Mo-Kα and Cu-Kα radiations with fully automated wavelength switching. It is an auto crystal structure solving system and used for 3D structure determination from single crystals in structural biology and chemical crystallography.

Applications:

1. Determination of phase purity, unit cell parameters, atomic coordinates, crystal system and space group
2. 3-D structure of the molecule that provides the absolute configuration and the intermolecular interaction.
3. Structure based drug design understanding the conformational space and molecular flexibility.
4. Biological crystallography in detection of protein and DNA structure.

Software used:

1. APEX3 for data collection.
2. SHEXLTL for structure confirmation and refinement.