Indian Institute of Technology Guwahati
Department of Biosciences and Bioengineering

Stem Cell and Cancer Biology Group
 

Publications

 

1.Anupam Bharadwaj, Ranjan Kalita, Amalesh Kumar, Anupam Sarma, Bithiah G. Jaganathan, Sunil Kumar, Frederik Gorlitz, Jonathan Lightley, Chris Dunsby, Mark Neil, Callum Hollick, Jeremy Graham, P. M. W. French, Bosanta R. Boruah. A cost-effective, modular, research-grade optical microscope. Current Science, Volume 126, Year 2024, Pages 244-2554, DOI:10.18520/cs/v126/i2/244-254

2. Anupam Bharadwaj, Amalesh Kumar, Ranjan Kalita, Rumela Mitra, Amit Sharma, Bithiah Grace Jaganathan, Jina Bhattacharyya, Anupam Sarma, Edwin Garcia, Sunil Kumar, Jonathon Lightley, Yuriy Alexandrov, Christopher Dunsby, Mark Neil, P M W French and Bosanta R Boruah. Super-resolved fluorescence imaging utilising accessible stochastic optical reconstruction microscopy (easySTORM) implemented on a low-cost, modular open-source (openFrame) microscope. Measurement Science and Technology, Volume 35, Year 2024, DOI:10.1088/1361-6501/ad761b

3. Anupam Bharadwaj, Amalesh Kumar, Sam Padalumavunkal Mathew, Rumela Mitra, Jina Bhattacharyya, Bithiah Grace Jaganathan*, Bosanta R. Boruah*. Advancing cellular insights: Super-resolution STORM imaging of cytoskeletal structures in human stem and cancer cells. Biochemistry and Biophysics Reports, Volume 39, Year 2024, DOI:10.1016/j.bbrep.2024.101798

4. Amalesh Kumar, Anupam Bharadwaj, Pranjal Choudhury, Sam P. Mathew, Bithiah Grace Jaganathan, Bosanta R. Boruah. Tuning the excitation laser power in a stochastic optical reconstruction microscope for Alexa Fluor 647 dye in Vectashield mounting media. Review of Scientific Instruments, Volume 95, Year 2024, DOI:10.1063/5.0217409

5. Anupam Bharadwaj, Amalesh Kumar, Rumela Mitra, Bithiah Grace Jaganathan and Bosanta R Boruah. Enhanced fluorescence blinking of AF647 fluorophores in Mowiol via violet and UV light induced recovery for superior localization microscopy. Methods and Applications in Fluorescence, Volume 12, Year 2024, DOI:10.1088/2050-6120/ad4ae6

6. Kaushik Kumar Bharadwaj, Bijuli Rabha, Iqrar Ahmad, Chandra Kanta Bhattacharjee, Bithiah Grace Jaganathan, Snikdha Poddar, Harun Patel, Vetriselvan Subramaniyan, Suresh V. Chinni, Gobinath Ramachawolran, Rasha Saleem, Eman Hussain Khalifa Ali, Mohamed M. Abdel-Daim, Debabrat Baishya, Arabinda Ghosh. Rhamnetin, a nutraceutical flavonoid arrests cell cycle progression of human ovarian cancer (SKOV3) cells by inhibiting the histone deacetylase 2 protein. Journal of Biomolecular Structure and Dynamics, Year 2023, DOI:10.1080/07391102.2023.2275187

8.  Rumela Mitra, Bithiah Grace Jaganathan
* (2023). CD90 in Cancer Progression, Metastasis and Chemoresistance. Book Chapter

8. Rumela Mitra, M. Aswanth Harish, Bithiah Grace Jaganathan
* (2023). Studying the Role of ERK Inhibition in Glioblastoma Multiforme. In: Pandey, L.M., Gupta, R., Thummer, R.P., Kar, R.K. (eds) Healthcare Research and Related Technologies. NERC 2022. Springer, Singapore. https://doi.org/10.1007/978-981-99-4056-1_7
 
9. Soumik Pal, Amit Sharma, Sam P Mathew, Bithiah Grace Jaganathan
* (2022). Targeting cancer-specific metabolic pathways for developing novel cancer therapeutics. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.955476. [Article

10. Rumela Mitra, Ayushi Rehman, Kusum K Singh
*, Bithiah Grace Jaganathan*. Multifaceted roles of MAGOH Proteins. Mol Biol Rep (2022). https://doi.org/10.1007/s11033-022-07904-1. [Article

11. Renu Sharma, Gayatri Gogoi, Snigdha Saikia, Amit Sharma, Deep Jyoti Kalita, Anupam Sarma, Anil Mukund Limaye, Manish Kumar Gaur, Jina Bhattacharyya, Bithiah Grace Jaganathan*. BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling. J Cell Commun Signal. 2021. https://doi.org/10.1007/s12079-021-00649-9. [Article

12. Amit Sharma, Bithiah Grace Jaganathan*. Stem Cell Therapy for Retinal Degeneration: The Evidence to Date. Biologics. 2021;15:299-306. [Article

13. Sachin Thomas, Bithiah Grace Jaganathan*. Signaling network regulating osteogenesis in mesenchymal stem cells. J Cell Commun Signal. 2021 Jul 8. doi: 10.1007/s12079-021-00635-1. Epub ahead of print. PMID: 34236594. [Article

14. Amit Sharma, Anuja Chakraborty, Bithiah Grace Jaganathan*. Review of the potential of mesenchymal stem cells for the treatment of infectious diseases. World J Stem Cells (2021); 13(6): 568-593. [DOI: 10.4252/wjsc.v13.i6.568] [Article]

15. Sanjucta Adak, Damaris Magdalene, Saurabh Deshmukh, Dipankar Das, Bithiah Grace Jaganathan*. A Review on Mesenchymal Stem Cells for Treatment of Retinal Diseases. Stem Cell Rev and Rep (2021). https://doi.org/10.1007/s12015-020-10090-x. [Article

16. Sreeja Dattachoudhury, Renu Sharma, Atul Kumar, Bithiah Grace Jaganathan*. Sorafenib Inhibits Proliferation, Migration and Invasion of Breast Cancer Cells. Oncology. 2020;98(7):478-486. doi: 10.1159/000505521. Epub 2020 May 20. [Article

17. Atul Kumar, Renu Sharma, Sreeja Dattachoudhury, Amit Sharma, Trishna Anand, Jina Bhattacharyya, Kasturi Bhattacharjee, Bithiah Grace Jaganathan*. OCT4A transcript level correlates with proliferation potential of human mesenchymal stem cells.  Gene reports (2019) https://doi.org/10.1016/j.genrep.2019.100459. [Article

18.
Darilang Mawrie, Kasturi Bhattacharjee, Amit Sharma, Renu Sharma, Jina Bhattacharyya, Harsha Bhattacharjee, Nilutparna Deori, Atul Kumar, Bithiah Grace Jaganathan*. Human orbital adipose tissue-derived mesenchymal stem cells possess neuroectodermal differentiation and repair ability. Cell Tissue Res. 2019 Aug 3. doi: 10.1007/s00441-019-03072-0.  [Article] 

19. Renu Sharma, Amit Sharma, Atul Kumar*, Bithiah Grace Jaganathan*. Phospho-protein Analysis in Adherent Cells Using Flow Cytometry (2019) Bio-protocol 9(20): e3395. DOI: 10.21769/BioProtoc.3395. [Article

20. Amit Sharma, Darilang Mawrie, Damarais Magdalene* and Bithiah Grace Jaganathan*. Isolation of Multipotent Mesenchymal Stem Cells from Human Extraocular Muscle Tissue (2019) Bio-protocol 9(4): e3167. DOI: 10.21769/BioProtoc.3167.  [Article]

21. Chinnapaka Somaiah#, Atul Kumar#, Renu Sharma#, Amit Sharma, Trishna Anand, Jina Bhattacharyya, Damodar Das, Sewali Deka Talukdar, Bithiah Grace Jaganathan*. Mesenchymal stem cells show functional defect and decreased anti-cancer effect after exposure to chemotherapeutic drugs.  J Biomed Sci. 2018; 25: 5. doi: 10.1186/s12929-018-0407-7 [Article

22. Atul Kumar, Trishna Anand, Jina Bhattacharyya, Amit Sharma, Bithiah Grace Jaganathan*. K562 chronic myeloid leukemia cells modify osteogenic differentiation and gene expression of bone marrow stromal cells. J. Cell Commun. Signal.  (2017). https://doi.org/10.1007/s12079-017-0412-8. [Article]  

23. Atul Kumar, Jina Bhattacharyya, Bithiah Grace Jaganathan*. Adhesion to stromal cells mediates imatinib resistance in chronic myeloid leukemia through ERK and BMP signaling pathways. Scientific Reports 7, 9535 (2017). doi:10.1038/s41598-017-10373-3. [Article]  

24. Darilang Mawrie#, Atul Kumar#, Damaris Magdalene, Jina Bhattacharyya, Bithiah Grace Jaganathan*. Mesenchymal stem cells from human extra ocular muscle harbor neuroectodermal differentiation potential. 2016.  PLoS One 11(6): e0156697. doi:10.1371/journal.pone.0156697. [Article]  

25. Atul Kumar#, Anshuman Bhanja#, Jina Bhattacharyya, Bithiah Grace Jaganathan*. Multiple roles of CD90 in cancer. Tumor Biol. (2016) 37: 11611. https://doi.org/10.1007/s13277-016-5112-0. [Article]

26. Chinnapaka Somaiah, Atul Kumar, Darilang Mawrie, Amit Sharma, Suraj Patil, Jina Bhattacharyya, R. Swaminathan, Bithiah Grace Jaganathan*. Collagen promotes higher adhesion, survival and proliferation of mesenchymal stem cells. 2015. PLoS One 10(12): e0145068. doi:10.1371/journal.pone.0145068. [Article]

27.
Himangshu Sonowal, Atul Kumar, Jina Bhattacharyya, Pabitra Kumar Gogoi, Bithiah Grace Jaganathan*. Inhibition of actin polymerization decreases osteogeneic differentiation of mesenchymal stem cells through p38 MAPK pathway. J Biomed Sci. 2013 Sep 26;20(1):71. [Article]  

28. Bithiah Grace Jaganathan*, Fernando Anjos-Afonso, Atul Kumar, Dominique Bonnet*. Active RHOA favors retention of human hematopoietic stem/progenitor cells in the niche. J Biomed Sci. 2013 Sep 11;20(1):66. doi: 10.1186/1423-0127-20-66. [Article]  

29. Bithiah Grace Jaganathan, Dominique Bonnet. Human Mesenchymal Stem Cells Senesce with Exogenous OCT4.  Cytotherapy. 2012 Oct;14(9):1054-63. doi: 10.3109/14653249.2012.697145. [Abstract]  

30. Bithiah Grace Jaganathan, Veronica Tisato, Thomas Vulliamy, Inderjeet Dokal, Judith Marsh, Francesco Dazzi, Dominique Bonnet. Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation.  Leukemia. 2010 Oct;24(10):1791-5. doi: 10.1038/leu.2010.164. [Abstract]

31. Bithiah Grace Jaganathan, Brigitte Ruester, Lars Dressel, Stefan Stein, Manuel Grez, Erhard Seifried, Reinhard Henschler. Rho inhibition induces migration of mesenchymal stromal cells. Stem Cells. 2007 Aug;25(8):1966-74. [Abstract]  

32. Stephan Gottig, Dietrich Moebest, Brigitte Ruster, Bithiah Grace, Sylvia Winter, Erhard Seifried, Jens Gille, Thomas Wieland, Reinhard Henschler. Role of monomeric GTPase Rho in hematopoietic progenitor cell migration and transplantation. Eur J Immunol. Jan 2006, Vol. 36, Issue 1:180-9. [Article]  

33. Brigitte Ruester#, Bithiah Grace#, Oliver Seitz, Erhard Seifried, Reinhard Henschler. Induction and Detection of Human Mesenchymal Stem Cell Migration in the 48-Well Reusable Transwell Assay. Stem Cells Dev. 2005 Apr;14(2):231-5. [Abstract]  


# Equal contribution

* Corresponding author 

 

 

 

 

 
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