Welcome to
     Biological Chemistry Laboratory
                                     ... webpage of  Dr. Debasis Manna

Doctoral Research Position:
Interested candidates with CSIR/GATE fellowship can directly mail to dmanna@iitg.ac.in for Ph.D. positions.

Post Doctoral Research Position:
Applicants are encouraged to arrange their own  postdoctoral fellowships from DST, CSIR, UGC, DAE, DBT and other funding agencies.
Recent Pubations
Photoswitchable Inhibitors: Temporally Regulated Inhibition of IDO1 Enzyme Using Photoactive Merocyanine Derivatives, Das, N. M., Biswas, S., Chauhan, S., Sahoo, A., Dhabal, D., Manna, D.* Chemical Communications, 2025, Just Accepted

Supramolecular Ion Channels To Engineer Zn2+ Ion Transport Mediated Chemical-to-Optical Signal Transduction, Srimayee, S., Prusty, B. M., Kar, M., Winterhalter, M.,* Manna, D.* Angewandte Chemie, 2025, 64, e202501634.

ß-Carboline-based light and pH dual stimuli-responsive ion transporters induce cancer cell death, Kar, K. M., Mahata, R., Srimayee, S., Haloi, N., Kumar, R., Lindahl, E., Santra, K. M., Manna, D.*, Chemical Communications, 2024, 60, 8419-8422.

Sulfonium-cross-linked Hyaluronic acid-based Self-healing Hydrogel: Stimuli-responsive Drug Carrier with Inherent Antibacterial Activity to Counteract Antibiotic-Resistant Bacteria, Patel, A., Goswami, S., Hazarika, G., Sivaprakasam, S., Bhattacharjee, S., Manna, D.*, Advanced Healthcare Materials, 2024, 3, 2302790.

Stimuli-responsive release of active anionophore from RGD-peptide-linked proanionophore, Srimayee, S., Badajena, R. S., Akhtar, N., Kar, K. M., Dey, S., Mohapatra. P.,* Manna, D.* Chemical Communications, 2023, 59, 12759-12762.

Stimuli-responsive assembly and disassembly of anionic suprasomes with tunable antibacterial activity, Prusty, B. M., Karn, R., Patel, A., Mazumder, P., Kumar, S., Manna, D* Chemical Communications, 2023, 59, 10624-10627.

Quinoline Thiourea-Based Zinc Ionophores with Antibacterial Activity, Dey, S., Patel, A., Haloi, N., Srimayee, S., Paul, S., Barik, G. K., Akhtar, N., Shaw, D., Hazarika, G., Prusty, B. M., Kumar, M., Santra, M. K., Tajkhorshid, E.*, Bhattacharjee, S.*, and Manna, D.* Journal of Medicinal Chemistry, 2023, 66, 11078-11093.

Transmembrane fluoride anion transport by meso-3,5-bis(trifluoromethyl)phenyl picket calix[4]pyrrole, Patra, A. K., Srimayee, S., Halder, D., Roy, A., Mukherjee, S., Kundu, S., Hossain, M., Saha, R., Lee, C.H., Manna, D.*,  Saha, I* Chemical Communications, 2023, 59, 7407-7410.










Group Activities
We are a research group dedicated to the exciting fields of biological chemistry and supramolecular chemistry. Our current projects include developing synthetic ion transporters, which have the potential to revolutionize cellular communication and transmembrane ion transport processes. We are also working on liposomal drug delivery systems to improve the effectiveness of therapeutic agents. Additionally, our efforts encompass drug discovery and the promising field of immunotherapy, where we aim to harness the body's own immune system to combat cancer and other diseases.