• Khyati Raina

    M.Sc. Stem Cell and Tissue Engineering, Panjab University, Chandigarh, India

    Awards:

      • Awarded a travel grant for "Training program in Generation and Maintenance of Human iPS cells" organized by "The Accelerating the Application of Stem Cell Technology in Human Diseases (ASHD)" program supported by the Department of Biotechnology (DBT), Government of India, and The Centre for iPS Cell Research and Application (CiRA), Kyoto University, Japan, from 20th to 26th November 2019.

      Weblink: https://www.ncbs.res.in/adbs/blog/indo-japan-collaboration-program-enables-special-training-indian-researchers-ipsc-technology

    • • Awarded a travel grant by Science and Engineering Research Board-Department of Science and Technology (SERB-DST), Government of India for participating in the International meeting organized by "International Society for Stem Cell Research (ISSCR)” from 14th to 17th June, 2023 at Boston, Massachusetts, USA.

      • Workshop:

      • Participated in a workshop on "CRISPR-Cas9 based precise genome editing" organized and hosted by "CSIR-Institute of Genomics and Integrative Biology" at New Delhi, India from 8th to 12th April, 2019.

      Conference/Symposium:

      • Participated in India|EMBO symposium on "Regulatory epigenomics: From large data to useful models" with a poster at Chennai, India from 10th to 13th March, 2019.

      Publications ▼

      Publications (from SCERM Lab):

        • Raina K, Joshi G, Modak K, Premkumar C, Priyanka S, Rajesh P, Velayudhan SR, Thummer RP (2023). Generation and characterization of induced pluripotent stem cell line IITGi001-A derived from adult human primary dermal fibroblasts. Stem Cell Research. https://doi.org/10.1016/j.scr.2023.103159

        • Dey, C., Raina K, Thummer, R.P. (2023). Production of a Bioactive Recombinant Human UTF1 Protein from E. coli. Healthcare Research and Related Technologies. NERC 2022. In: Pandey, L.M., Gupta, R., Thummer, R.P., Kar, R.K. (eds) Springer, Singapore. https://doi.org/10.1007/978-981-99-4056-1_4

        • Subhendu SS, Bora A, Golder A, Raina K, Haridhasapavalan KK, Thummer RP (2022) Gelatin-PVA-AgNPs triad composite as wound healing hydrogel with wounded skin surface protective efficiency, SSRN Electronic Journal, http://dx.doi.org/10.2139/ssrn.4219683 (Elsevier).

        • Banerjee K, Bhattacherjee D, Raina K, Thummer RP, Bhabak KP (2022) Benzimidazole-based ionic and non-ionic organoselenium compounds: innovative synthetic strategies, structural characterization and preliminary anti-proliferative activities. New Journal of Chemistry, 46(24):11910-26. 10.1039/D2NJ01322C (Royal Society of Chemistry).

        • Bhattacherjee D, Raina K, Mandal T K, Thummer RP, Bhabak KP (2022) Targeting Wnt/β-catenin Signaling Pathway in Triple-negative Breast Cancer by Benzylic Organotrisulfides: Contribution of the Released Hydrogen Sulfide towards Potent Anti-Cancer Activity. Free Radical Biology and Medicine.

        • Sundaravadivelu PK, Raina K, Thool M, Ray A, Joshi JM, Kaveeshwar V, Sudhagar S, Lenka N, Thummer RP (2021) Tissue-restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature). https://doi.org/10.1007/5584_2021_660

        • Ray A*, Joshi JM*, Sundaravadivelu PK*, Raina K, Lenka N, Kaveeshwar V, Thummer RP (2021) An overview on promising somatic cell sources utilized for the efficient generation of induced pluripotent stem cells. Stem Cell Reviews and Reports. https://doi.org/10.1007/s12015-021-10200-3 *Equal contribution.

        • Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution.

        • Raina K, Dey C, Thool M, Sudhagar S, Thummer RP (2021) An insight into the role of UTF1 in development, stem cells, and cancer. Stem Cell Reviews and Reports. doi: 10.1007/s12015-021-10127-9 (Springer Nature).

        • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. https://doi.org/10.1007/s00449-021-02516-8 (Springer Nature).

        • Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution.

        • Haridhasapavalan KK*, Raina K*, Dey C*, Adhikari P, Thummer RP (2020) An Insight into Reprogramming Barriers to iPSC Generation. Stem Cell Rev and Rep. 16(1): 56-81. doi: 10.1007/s12015-019-09931-1 (Springer Nature). *Equal contribution

        • Dey S, Patel A, Raina K, Pradhan N, Biswas O, Thummer RP$, Manna D (2020) Stimuli-Responsive Anticancer Drug Delivery System with Inherent Antibacterial Activities. Chemical Communications. 56(11): 1661-1664. doi:10.1039/c9cc08834b. $ Corresponding Author

        Publications (from other Labs):

        • Mahajan N, Raina K, Gupta A (2019) High fructose induced adipogenesis and inhibitory potential of tigonelline on murine mesenchymal stem cells: a morphological study. IJPSR, 2019; Vol.10(2):528-536.

    Meeting with Prof. Shinya Yamanaka (Nobel Laureate in Physiology or Medicine 2012) by "Accelerating the applications of Stem cell technology in Human Diseases (ASHD)" program supported by Department of Biotechnology (DBT), Government of India and the Centre for iPS cell Research and Application (CiRA), Kyoto University, Japan.


PhD Student

Year of joining: January, 2018
Research Project: Investigating the role of human UTF1 in reprogramming, self-renewal and differentiation using a CRISPR/Cas toolbox
Email ID: raina.khyati@iitg.ac.in
Research Gate ID


PhD Student

Year of joining: January, 2016
Research Project: Cell Therapy for Cardiovascular diseases
Email ID: hk.kumar@iitg.ac.in
Research Gate ID

  • H Krishna Kumar

    Post Doctoral Fellow, University of Pennsylvania, USA

    Awards:

    • Augmenting Writing Skills for Articulating Research (AWSAR) Award 2021: Awarded for the best scientific story writing titled "Love failure may or may not be fixed, but heart failure can definitely be fixed", which includes a prize of ₹10,000/- along with a Certificate of Appreciation. The story will be published later in the book "AWSAR Awarded Popular Science Articles by Scientists for the People- 2021" by the Department of Science and Technology, Government of India. https://www.awsar-dst.in/results-2021.

    Publications ▼

    Publication (from SCERM Lab):

    • Haridhasapavalan KK, Borthakur A, Thummer RP (2023) Direct cardiac reprogramming: Current status and future prospects. Sub-series: Cell Biology and Translational Medicine. Series: Advances in Experimental Medicine and Biology (Springer Nature), https://doi.org/10.1007/5584_2022_760 (IF: 3.650).

    • Haridhasapavalan KK, Sundaravadivelu PK, Voorkara U, Kaveeshwar V, Thummer RP (2023) Generation of recombinant version of a bioactive human MEF2C transcription factor from E. coli, Healthcare Research and Related Technologies - Proceedings of NERC 2022 (Springer Nature).

    • Subhendu SS, Bora A, Golder A, Raina R, Haridhasapavalan KK, Thummer RP (2022) Gelatin-PVA-AgNPs triad composite as wound healing hydrogel with wounded skin surface protective efficiency, SSRN Electronic Journal, http://dx.doi.org/10.2139/ssrn.4219683 (Elsevier).

    • Haridhasapavalan KK, Sundaravadivelu PK, Joshi N, Das NJ, Mohapatra A, Voorkara U, Kaveeshwar V, Thummer RP (2022) Generation of a recombinant version of a biologically active cell-permeant human HAND2 transcription factor from E. coli, Scientific Reports, 10.1038/s41598-022-19745-w (Springer Nature) .

    • Haridhasapavalan KK, Das NJ, Thummer RP (2022) Generation of a transducible version of a bioactive recombinant human TBX5 transcription factor from E. coli. Current Research in Biotechnology, 4: 66-77. https://doi.org/10.1016/j.crbiot.2022.01.004 (Elsevier).

    • Haridhasapavalan KK, Harsh Ranjan S, Bhattacharyya S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human MESP1 transcription factor. Applied Microbiology and Biotechnology, 105(6), 2363-2376. https://doi.org/10.1007/s00253-021-11194-1 (Springer Nature)

    • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. https://doi.org/10.1007/s00449-021-02516-8 (Springer Nature).

    • Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution, Invited Book Chapter.

    • Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution, Invited Book Chapter

    • Haridhasapavalan KK*, Sundaravadivelu PK*, Thummer RP (2020) Codon Optimization, Cloning, Expression, Purification, and Secondary Structure Determination of Human ETS2 Transcription Factor. Molecular Biotechnology, 62(10), 485-494. https://doi.org/10.1007/s12033-020-00266-8 (Springer Nature). *Equal contribution.

    • Haridhasapavalan KK*, Raina K*, Dey C*, Adhikari P, Thummer RP (2020) An Insight into Reprogramming Barriers to iPSC Generation. Stem Cell Reviews and Reports. 16(1): 56-81. doi: 10.1007/s12015-019-09931-1 (Springer Nature). *Equal contribution.

    • Borgohain MP*, Haridhasapavalan KK*, Dey C, Adhikari P, Thummer RP (2019) An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Stem Cell Reviews and Reports. 15(2): 286-313. doi: 10.1007/s12015-018-9861-6 (Springer Nature). *Equal contribution.

    • Haridhasapavalan KK*, Borgohain MP*, Dey C, Saha B, Narayan G, Kumar S, Thummer RP (2019) An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells. Gene. 686:146-159. https://doi.org/10.1016/j.gene.2018.11.069 (Elsevier). *Equal contribution.

    • Saha B, Krishna Kumar H, Borgohain MP, Thummer RP (2018) Prospective applications of Induced Pluripotent Stem Cells in Military Medicine. Med J Armed Forces India. 74(4): 313-320. https://doi.org/10.1016/j.mjafi.2018.03.005 (Elsevier)

    • Borgohain MP*, Narayan G*, Krishna Kumar H, Dey C, Thummer RP (2018) Maximizing Expression and Yield of Human Recombinant Proteins from Bacterial Cell Factories for Biomedical Applications. Advances in Microbial Biotechnology: Current Trends and Future Prospects. Apple Academic Press. ISBN: 9781771886673. *Equal contribution.

    • Dey C*, Narayan G*, Krishna Kumar H*, Borgohain MP*, Lenka N, Thummer RP (2017) Cell-Penetrating Peptides as a Tool to Deliver Biologically Active Recombinant Proteins to Generate Transgene-Free Induced Pluripotent Stem Cells. Stud Stem Cells Res Ther 3(1): 006-015. *Equal contribution. DOI: 10.17352/sscrt.000011

  • Chandrima Dey

    M.Sc. Biotechnology, Vellore Institute of Technology, Vellore, Tamil Nadu, India

    Awards:

    Publications ▼

    Publication (from SCERM Lab):

    • Dey C, Venkatesan V, Thummer RP (2022) Identification of optimal expression parameters and purification of a codon-optimized human GLIS1 transcription factor from Escherichia coli. Molecular Biotechnology, 64(1):42-56. https://doi.org/10.1007/s12033-021-00390-z (Springer Nature).

    • Dey C*, Thool M*, Bhattacharyya S, Sudhagar S, Thummer RP (2021) Generation of biologically active recombinant human OCT4 protein from E. coli. 3 Biotech, 11(5), 207. https://doi.org/10.1007/s13205-021-02758-z (Springer Nature). *Equal contribution.

    • Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution, Invited Book Chapter.

    • Thool M*, Dey C*, Sudhagar S, Thummer RP (2021) Generation of a recombinant stem cell-specific human SOX2 protein from Escherichia coli under native conditions. Molecular Biotechnology, 63(4), 327-338. https://link.springer.com/article/10.1007/s12033-021-00305-y (Springer Nature). *Equal contribution.

    • Raina K, Dey C, Thool M, Sudhagar S, Thummer RP (2021) An insight into the role of UTF1 in development, stem cells, and cancer. Stem Cell Reviews and Reports. doi: 10.1007/s12015-021-10127-9 (Springer Nature).


      Dey C      *, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution, Invited Book Chapter

    • Haridhasapavalan KK*, Raina K*, Dey C*, Adhikari P, Thummer RP (2020) An Insight into Reprogramming Barriers to iPSC Generation. Stem Cell Rev and Rep. 16(1): 56-81. doi: 10.1007/s12015-019-09931-1 (Springer Nature). *Equal contribution.

    • Borgohain MP*, Haridhasapavalan KK*, Dey C, Adhikari P, Thummer RP (2019) An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Stem Cell Rev and Rep. 15(2): 286-313. doi: 10.1007/s12015-018-9861-6 (Springer Nature). *Equal contribution.

    • Haridhasapavalan KK*, Borgohain MP*, Dey C, Saha B, Narayan G, Kumar S, Thummer RP (2019) An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells. Gene. 686:146-159. https://doi.org/10.1016/j.gene.2018.11.069 (Elsevier). *Equal contribution.

    • Saha B, Borgohain MP, Dey C, Thummer RP (2018) iPS Cell Generation: Current and Future Challenges. Ann Stem Cell Res Ther. 1(2): 1007.

    • Borgohain MP*, Narayan G*, Krishna Kumar H, Dey C, Thummer RP (2018) Maximizing Expression and Yield of Human Recombinant Proteins from Bacterial Cell Factories for Biomedical Applications. Advances in Microbial Biotechnology: Current Trends and Future Prospects. Apple Academic Press. ISBN: 9781771886673. *Equal contribution.

    • Dey C*, Narayan G*, Krishna Kumar H*, Borgohain MP*, Lenka N, Thummer RP (2017) Cell-Penetrating Peptides as a Tool to Deliver Biologically Active Recombinant Proteins to Generate Transgene-Free Induced Pluripotent Stem Cells. Stud Stem Cells Res Ther 3(1): 006-015. *Equal contribution. DOI: 10.17352/sscrt.000011

    Publication (from other Labs):

    • Doss H M, Dey C, Sudandiradoss C, Rasool M K (2016) Targeting inflammatory mediators with ferulic acid, a dietary polyphenol, for the suppression of monosodium urate crystal-induced inflammation in rats, Life Sciences, Vol.148, Pages 201-210.

    Meeting with Prof. Shinya Yamanaka (Nobel Laureate in Physiology or Medicine 2012) organized by "The Accelerating the application of Stem cell technology in Human Diseases (ASHD)" program supported by Department of Biotechnology (DBT), Government of India and The Centre for iPS Cell Research and Application (CiRA), Kyoto University, Japan.


PhD Student

Year of joining: July, 2016
Research Project: Stem Cell Therapy for Cardiovascular diseases
Email ID: dey.chandrima@iitg.ac.in
Research Gate ID


PhD Student

Year of joining: July, 2016
Research Project: Cell Therapy for Diabetes Mellitus
Email ID: gloria@iitg.ac.in
Research Gate ID

  • Gloria Narayan

    M.Tech Biotechnology, National Institute of Technology Rourkela, Rourkela, Odisha, India

    Conference/Workshop:

    • Participated in a workshop on "Human induced pluoripotent stem cells (iPSCs)" organized by "Centre for stem cell research" , Christian Medical Colllege Campus, Bagayam, Vellore from 18th to 23rd February, 2019.

    Publications ▼

    Publication (from SCERM Lab):

    • Narayan G, Ronima KR, Thummer RP (2022) Direct reprogramming of somatic cells into induced β-cells: An Overview. Sub-series: Cell Biology and Translational Medicine. Series: Advances in Experimental Medicine and Biology (Springer Nature), https://doi.org/10.1007/5584_2022_756 (IF: 3.650)

    • Narayan G, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Protein production and purification of a codon-optimized human NGN3 transcription factor from E. coli. Protein Journal, 40(6):891-906. https://doi.org/10.1007/s10930-021-10020-x (Springer Nature).

    • Agrawal A*, Narayan G*, Gogoi R, Thummer RP (2021) Recent advances in the generation of β-cells from induced pluripotent stem cells as a potential cure for diabetes mellitus. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature). *Equal contribution.

    • Narayan G, Sundaravadivelu PK, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor. Protein Expression and Purification, 180: 105807. https://doi.org/10.1016/j.pep.2020.105807 (Elsevier).

    • Haridhasapavalan KK*, Borgohain MP*, Dey C, Saha B, Narayan G, Kumar S, Thummer RP (2019) An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells. Gene. 686:146-159. https://doi.org/10.1016/j.gene.2018.11.069 (Elsevier). *Equal contribution.

    • Borgohain MP*, Narayan G*, Krishna Kumar H, Dey C, Thummer RP (2018) Maximizing Expression and Yield of Human Recombinant Proteins from Bacterial Cell Factories for Biomedical Applications. Advances in Microbial Biotechnology: Current Trends and Future Prospects. Apple Academic Press. ISBN: 9781771886673. *Equal contribution.

    • Dey C*, Narayan G*, Krishna Kumar H*, Borgohain MP*, Lenka N, Thummer RP (2017) Cell-Penetrating Peptides as a Tool to Deliver Biologically Active Recombinant Proteins to Generate Transgene-Free Induced Pluripotent Stem Cells. Stud Stem Cells Res Ther 3(1): 006-015. *Equal contribution. DOI: 10.17352/sscrt.000011

  • Ms. Madhuri Thool

    • Student as Co-Supervisor

    NIPER Guwahati, Guwahati, Assam, India

    Publications ▼

    Publications (from SCERM Lab):

    • Thool M, Sundaravadivelu PK, Sudhagar S, Thummer RP (2022) A Comprehensive Review on the Role of ZSCAN4 in Embryonic Development, Stem Cells, and Cancer. Stem Cell Reviews and Reports. Jun 23:1-7. https://doi.org/10.1007/s12015-022-10412-1 (Springer Nature).

    • Sundaravadivelu PK, Raina K, Thool M, Ray A, Joshi JM, Kaveeshwar V, Sudhagar S, Lenka N, Thummer RP (2021) Tissue-restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature).

    • Dey C*, Thool M*, Bhattacharyya S, Sudhagar S, Thummer RP (2021) Generation of biologically active recombinant human OCT4 protein from E. coli. 3 Biotech, 11(5), 207. https://doi.org/10.1007/s13205-021-02758-z (Springer Nature). *Equal contribution.

      Dey C      *, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution, Invited Book Chapter.

    • Thool M*, Dey C*, Sudhagar S, Thummer RP (2021) Generation of a recombinant stem cell-specific human SOX2 protein from Escherichia coli under native conditions. Molecular Biotechnology, 63(4), 327-338. https://link.springer.com/article/10.1007/s12033-021-00305-y (Springer Nature). *Equal contribution.

    • Raina K, Dey C, Thool M, Sudhagar S, Thummer RP (2021) An insight into the role of UTF1 in development, stem cells, and cancer. Stem Cell Reviews and Reports. doi: 10.1007/s12015-021-10127-9 (Springer Nature).

      Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution, Invited Book Chapter

PhD student

Supervisor: Dr. S Sudhagar
Co-Supervisor: Dr. Rajkumar P. Thummer

Year of joining: November, 2018
Email ID: madhuri.thool@niperguwahati.ac.in

PhD student

Supervisor: Dr. Shirisha Nagotu
Co-Supervisor: Dr. Rajkumar P. Thummer

Year of joining: January, 2016
Email ID: d.nayan@iitg.ac.in

Mr. Nayan Moni Deori

Indian Institute of Technology Guwahati, Guwahati, Assam, India

Publications ▼

Publications (from SCERM Lab):

  • Deori NM, Infant T, Thummer RP, Nagotu S (2022) Characterization of the multiple domains of Pex30 involved in subcellular localization of the protein and regulation of peroxisome number. Cell Biochemistry and Biophysics (Springer Nature), https://doi.org/10.1007/s12013-022-01122-z (IF: 2.989).

  • M.Tech Student

    Allan Blessing Harison Raj A

    B.Tech Biotechnology, Kamraj College of Engineering and Technology, Tamilnadu, India

    Publications ▼

    Publications (from SCERM Lab):

    Publications (from other Lab):

    • Manibalan, S., Harison Raj, A. B., & Achary, A. (2021). Screening of Atherosclerotic Druggable Targets from the Proteome Network of Differentially Expressed Genes. ASSAY and Drug Development Technologies, 19(5), 290-299.

Mtech Student

Year of joining: June, 2023
Research Project: Production of bioactive recombinant human ZSCAN4 protein from E. coli
Email ID: a.allan@iitg.ac.in
Research Gate ID


M.Tech. Student

Year of joining: May, 2021
Research Project:
Email ID: ronima.k@iitg.ac.in

  • Ronima K R

    Bachelor of Technology (Honours) in Biotechnology and Biochemical Engineering (2017-2021) - APJ Abdul Kalam Technological University, Kerala

    Publications ▼

    Publication (from SCERM Lab):

  • Tirthankar Sen

    M.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    • Sen T, Thummer RP (2022) The Impact of Human Microbiotas in Hematopoietic Stem Cell and Organ Transplantation. Frontiers in Immunology. Jul 7; 13:932228. https://doi.org/10.3389/fimmu.2022.932228.

      Sen T*, Thummer RP (2022) CRISPR and iPSCs: Recent Developments and Future Perspectives in Neurodegenerative Disease Modelling, Research, and Therapeutics (2022). Neurotoxicity Research, Aug 31:1-27, https://doi.org/10.1007/s12640-022-00564-w (Springer Nature).


M.Tech.

Year of joining: May, 2021
Research Project: Insilico analysis of stem cell-specific transcription factors
Email ID: tsen@iitg.ac.in
Current Position:


M.Tech.

Year of joining: May, 2021
Research Project: Insilico analysis of stem cell-specific transcription factors
Email ID: rishabh18b@iitg.ac.in
Current Position:  

  • Kumar Rishabh

    B.Tech Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India

  • Rahul Doshi

    B.Tech Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India


B.Tech.

Year of joining: May, 2021
Research Project: Insilico analysis of stem cell-specific transcription factors
Email ID: rahul@iitg.ac.in
Current Position:


M.Tech.

Year of joining: May, 2020
B.Tech. Project: Soluble expression, purification, secondary structure determination and in silico analysis of human PAX4 transcription factor
Email ID: a.akriti@iitg.ac.in
Current Position:
Research Gate ID

  • Akriti Agrawal

    M.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    Narayan G, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Protein production and purification of a codon-optimized human NGN3 transcription factor from E. coli. Protein Journal, 40(6):891-906. https://doi.org/10.1007/s10930-021-10020-x (Springer Nature).

    Agrawal A*, Narayan G*, Gogoi R, Thummer RP (2021) Recent advances in the generation of β-cells from induced pluripotent stem cells as a potential cure for diabetes mellitus. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature). *Equal contribution.

    Narayan G, Sundaravadivelu PK, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor. Protein Expression and Purification, 180: 105807. https://doi.org/10.1016/j.pep.2020.105807 (Elsevier).


B.Tech.

Year of joining: May, 2020
Research Project: Heterologous expression, purification, characterization and intra-cellular delivery of Human NANOG
Email ID: arnab170106013@iitg.ac.in
Current Position:
Research Gate ID


M.Tech.

Year of joining: May, 2020
B.Tech. Project: Expression, purification and characterization of recombinant ETS2
Email ID: s18@iitg.ac.in
Current Position: PhD, IIT Guwahati, Guwahati, India
Research Gate ID

  • Pradeep Kumar S

    M.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. https://doi.org/10.1007/s00449-021-02516-8 (Springer Nature).

    • Narayan G, Sundaravadivelu PK, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor. Protein Expression and Purification, 180: 105807. https://doi.org/10.1016/j.pep.2020.105807 (Elsevier)

    • Haridhasapavalan KK*, Sundaravadivelu PK*, Thummer RP (2020) Codon Optimization, Cloning, Expression, Purification, and Secondary Structure Determination of Human ETS2 Transcription Factor. Molecular Biotechnology, 62(10), 485-494. https://doi.org/10.1007/s12033-020-00266-8 (Springer Nature). *Equal contribution.

  • Nayan Jyoti Das

    B.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    • Haridhasapavalan KK, Das NJ, Thummer RP (2022) Generation of a transducible version of a bioactive recombinant human TBX5 transcription factor from E. coli. Current Research in Biotechnology, 4: 66-77. https://doi.org/10.1016/j.crbiot.2022.01.004 (Elsevier).


B.Tech.

Year of joining: May, 2019
B.Tech. Project: Expression, purification and characterization of recombinant TBX5
Email ID: nayannjddas@iitg.ac.in
Research Gate ID


B.Tech.

Year of joining: May, 2019
B.Tech. Project: Heterologous expression, purification, characterization and intra-cellular delivery of Human MESP1
Email ID: suvya131211@iitg.ac.in
Current Position: Business Analyst;
ClearTax, Bangalore, India
Research Gate ID

  • Sujal Harsh Ranjan

    B.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. https://doi.org/10.1007/s00449-021-02516-8 (Springer Nature).

      Haridhasapavalan KK, Harsh Ranjan S, Bhattacharyya S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human MESP1 transcription factor. Applied Microbiology and Biotechnology, 105(6), 2363-2376. https://doi.org/10.1007/s00253- 021-11194-1 (Springer Nature).

  • Poulomi Adhikari

    M.Tech Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Conference/Workshop:

    • Participated in a workshop on “Human induced pluoripotent stem cells (iPSCs)” organized by “Centre for stem cell research” , Christian Medical Colllege Campus, Bagayam, Vellore from 18th to 23rd February, 2019.

    Publications ▼

    Publication (from SCERM Lab):

      Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution, Invited Book Chapter.

      Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution, Invited Book Chapter

      Haridhasapavalan KK*, Raina K*, Dey C*, Adhikari P, Thummer RP (2020) An Insight into Reprogramming Barriers to iPSC Generation. Stem Cell Rev and Rep. 16(1): 56-81. doi: 10.1007/s12015-019-09931-1 (Springer Nature). *Equal contribution.

      Borgohain MP*, Haridhasapavalan KK*, Dey C, Adhikari P, Thummer RP (2019) An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Stem Cell Rev and Rep. 15(2): 286–313. doi: 10.1007/s12015-018-9861-6 (Springer Nature). *Equal contribution.

      Publication (from other Labs):

      • Adhikari P, Singhania M, Kumar GP, Vuppu S (2014) Antibacterial testing of two culinary medicinal plants from vit nursery. Der Pharmacia Lettre 6(6):331-334.


M.Tech.

Year of joining: May, 2018
Research Project: Cloning stem cell-specific reprogramming factors in a novel non-integrating viral vector
Email ID: poulomi174106001@iitg.ac.in
Current Position: PhD student;
Academia Sinica, Taipei City, Taiwan
Research Gate ID


B.Tech.

Year of joining: July, 2018
B.Tech. Project: Expression analysis of cell reprogramming transcription factor human GATA-3
Email ID: a.bhavsar@iitg.ac.in
Research Gate ID

  • Ashutosh Bhavsar

    B.Tech, Indian Institute of Technology Guwahati, Guwahati, Assam, India

  • Sankalita Paul

    M.Sc. Life Science, National Institute of Technology Rourkela, Rourkela, Odisha, India


Junior Research Fellow (JRF)

Year of joining: February, 2018
Research Project: Generation of transgene-free human induced pluripotent stem cells using non-genetic approaches for cell therapeutic applications
Email ID: paulsankalita@iitg.ac.in
Current Position: PhD student;
IISER Mohali, Chandigarh
Research Gate ID


Research Gate ID

  • Manash P Borgohain

    M.S. (Pharm) Pharmacology & Toxicology, NIPER Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    • Borgohain MP*, Haridhasapavalan KK*, Dey C, Adhikari P, Thummer RP (2019) An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Stem Cell Rev and Rep. 15(2): 286–313. doi: 10.1007/s12015-018-9861-6 (Springer Nature). *Equal contribution.

    • Haridhasapavalan KK*, Borgohain MP*, Dey C, Saha B, Narayan G, Kumar S, Thummer RP (2019) An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells. Gene. 686:146-159. https://doi.org/10.1016/j.gene.2018.11.069 (Elsevier). *Equal contribution.

    • Saha B, Krishna Kumar H, Borgohain MP, Thummer RP (2018) Prospective applications of Induced Pluripotent Stem Cells in Military Medicine. Med J Armed Forces India. 74(4): 313-320. https://doi.org/10.1016/j.mjafi.2018.03.005 (Elsevier)

    • Saha B, Borgohain MP, Dey C, Thummer RP (2018) iPS Cell Generation: Current and Future Challenges. Ann Stem Cell Res Ther. 1(2): 1007.

    • Borgohain MP*, Narayan G*, Krishna Kumar H, Dey C, Thummer RP (2018) Maximizing Expression and Yield of Human Recombinant Proteins from Bacterial Cell Factories for Biomedical Applications. Advances in Microbial Biotechnology: Current Trends and Future Prospects. *Equal contribution.

    • Dey C*, Narayan G*, Krishna Kumar H*, Borgohain MP*, Lenka N, Thummer RP (2017) Cell-Penetrating Peptides as a Tool to Deliver Biologically Active Recombinant Proteins to Generate Transgene-Free Induced Pluripotent Stem Cells. Stud Stem Cells Res Ther 3(1): 006-015. *Equal contribution. DOI: 10.17352/sscrt.000011

  • Bitan Saha

    M.Tech Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Publications ▼

    Publication (from SCERM Lab):

    • Haridhasapavalan KK*, Borgohain MP*, Dey C, Saha B, Narayan G, Kumar S, Thummer RP (2019) An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells. Gene. 686:146-159. https://doi.org/10.1016/j.gene.2018.11.069 (Elsevier). *Equal contribution.

    • Saha B, Krishna Kumar H, Borgohain MP, Thummer RP (2018) Prospective applications of Induced Pluripotent Stem Cells in Military Medicine. Med J Armed Forces India. 74(4): 313-320. https://doi.org/10.1016/j.mjafi.2018.03.005 (Elsevier)

    • Saha B, Borgohain MP, Dey C, Thummer RP (2018) iPS Cell Generation: Current and Future Challenges. Ann Stem Cell Res Ther. 1(2): 1007.


M.Tech Project Duration:
06/2017 - 05/2018
Research Project: Cloning and Expression of Codon Optimized Stem Cell-Specific Human Transcription Factor NANOG in a Bacterial System
Email ID: btnsaha@gmail.com
Current Position: PhD student;
National University of Singapore, Singapore
Research Gate ID


M.Tech Project Duration:
06/2016 - 05/2017
M.Tech Project: Analysis of stem cell and related patents, patenting laws and clinical trial regulations in India and other Asian countries.
Co-Supervisor: Prof. Latha Rangan
Current Position: Entrepreneur,
New Delhi

Research Gate ID

  • Ankit Narula

    M.Tech. Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India