Bio Process Analytical Technology (BIOPAT) Laboratory

Phone: +91-361-2582226 (O)

Email : senthilkumar[AT]iitg.ac.in

2020

47. Subbi Rami Reddy Tadi, Ganesh Nehru, Senthilkumar Sivaprakasam,Metabolic engineering of Bacillus megaterium for the enhanced β-alanine production”, EMBO Symposium Engineering meets evolution: Designing biological systems, January 30- February 1, 2020, IIT Madras, India

2019

46. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Integrated bioprocessing strategies for greener bio-economy: A cassava based Agri food Industry waste to sustainable monomer” Bioprocessing India International symposium on Agri Food resources, BPI-19, Dec 14-17, 2019 at Central Food Technological Research Institute (CSIR-CFTRI), Mysuru, India (Bioprocessing India 19- Best poster award).

45. Ganesh Nehru, Subbi Rami Reddy Tadi, Senthilkumar Sivaprakasam, Biosynthesis of heparosan, a precursor for heparin polysaccharide in recombinant Bacillus spp, International Symposium on Sustainable Polymers & Launch of SPSI-North East Chapter, August 23-25, 2019, IIT Guwahati, India

44. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Process Intensification strategies for optically pure D lactic acid: A Sustainable bio-based monomer production process”. International symposium on Sustainable Polymers, SPSI-19. Aug 23-25, 2019 at IIT Guwahati, India (American Chemical Society (ACS)- Best poster award)

43. Subbi Rami Reddy Tadi, Ganesh Nehru, Senthilkumar Sivaprakasam, “Production of 3-aminopropionic acid using metabolically engineered Bacillus megaterium whole-cell biocatalysis”, Recent Advancements in Biochemical Engineering and Biotechnology (RABEB -2019), March 15-16, 2019, IIT Varanasi, India (Won Best Poster Presentation Award)

2018

42. Ganesh Nehru, Subbi Rami Reddy Tadi, Senthilkumar Sivaprakasam. Development of a dual promoter expression system for production of heparosan in recombinant Bacillus sp. Bioprocessing INDIA 2018: Recent Advancements and Applications in Bioprocessing for Healthcare, Bioenergy and Environment, December 16-18, 2018, IIT Delhi, India

41. Subbi Rami Reddy Tadi, Ganesh Nehru, Senthilkumar Sivaprakasam. Metabolic engineering of Bacillus spp. for the production of Beta-alanine, a vitamin B5 precursor, 59th International Annual Conference of the Association of Microbiologists of India (AMI- 2018), December, 9-12, 2018, University of Hyderabad, India

40. Subbi Rami Reddy Tadi, Ganesh N, Senthilkumar Sivaprakasam. Over expression vof L-aspartate alpha decarboxylase enhances the 3-aminopropionic acid production in Bacillus spp. Bioprocessing INDIA 2018: Recent Advancements and Applications in Bioprocessing for Healthcare, Bioenergy and Environment, December 16-18, 2018, IIT Delhi, India

39. Som Dutt Ravindran, Subbi Rami Reddy Tadi, Senthilkumar Sivapraksam. Metabolic engineering of Bacillus spp for the enhanced production PHB, Bioprocessing INDIA 2018: Recent Advancements and Applications in Bioprocessing for Healthcare, Bioenergy and Environment, December 16-18, 2018, IIT Delhi, India

38. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Reactive distillation for D-Lactic Acid Purification: A Process intensifying tool for Biorefineries”, Advances in Sustainable Polymers, ASP-17, 4th International conference, Jan 8-11,2018 at Indian Institute of Technology Guwahati

2017

37. Rengesh Balakrishnan, Subbi Rami Reddy Tadi, Senthilkumar Sivaprakasam and Shyamkumar Rajaram, Kodo Millet Bran Residue: A Value-added Agro industrial Waste By-product for D (-) lactic acid production, Bioprocessing INDIA 2017: Recent trends in bioprocessing for healthcare, energy and environment, December 9-11, 2017, IIT Guwahati, India

36. Srikanth Katla, Bappa Karmakar, Subbi Rami Reddy Tadi, Naresh Mohan, B.Anand, Senthilkumar Sivaprakasam, Media Optimization and Batch Kinetics Studies for Recombinant Human Interferon alpha 2b Production by Pichia pastoris, The 13th Asian Congress on Biotechnology (ACB 2017) Bioinnovation and Bioeconomy, July 23-27, 2017, Khon Kaen, Thailand

35. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Cassava fibrous waste enzymatic hydrolysis and fermentation: A systematic monitoring and control by LabVIEW based interface” Starch update-Agbio-2017, 9th International conference on starch Technology, 27-28th February,2017, Bangkok International trade and Exhibition Centre organized by BIOTEC and NSTDA of Thailand

34. Rengesh Balakrishnan, Subbi Rami Reddy Tadi, Senthilkumar Sivaprakasam and Shyamkumar Rajaram, A Study on Acid and Enzymatic Hydrolysis of Millet Bran, Strain Screening and Effect of Neutralizing Agents on Fermentative Production of D-Lactic Acid, International Conference on Polymer Science and Technology (MACRO 2017), January 9-11, 2017, VSSC Trivandrum, India

2016

33. Subbi Rami Reddy Tadi, Satish Cingadi, Arun E.V.R., Saurav Prasad, Srikanth Katla, Senthilkumar Sivaprakasam. Technical feasibility and substrate inhibition study for the microbial production of optically pure D (-) lactic acid using sago industrial waste. Technologies to Eradicate and Control Industrial Pollution (TECIP-2016), October 21-22, 2016 Annamalai University, Chidambaram, India (Won Best Presentation Award)

32. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Sustainable utilization of Cassava based Industry waste for Stereospecific Lactic Acid precursors and its characterization” National conference for Technologies to eradicate and control industrial Pollution (TECIP-2016), 21-22nd October,2016 at Annamalai University, India (First prize for oral Presentation)

31. Kiran Kumar Gali, Vimal Katiyar and Senthilkumar Sivaprakasam, “Cassava fibrous waste as a sustainable feedstock for fermentable sugars: Characterization and emergy analysis” 252nd ACS National Meeting, August 21-25, 2016 Philadelphia, USA.

30. Subbi Rami Reddy Tadi, Saurav Prasad, Satish Cingadi, Srikanth Katla, Arun E.V.R., Senthilkumar Sivaprakasam. Renewable and economical agricultural feedstocks for the production of optically pure D (-) lactic acid by homo-fermentative lactic acid bacteria. 3rd International Symposium on Advances in Sustainable Polymers (ASP-16), August 4-6, 2016, Kyoto Institute of Technology, Kyoto, Japan

29. Kiran Kumar Gali, Kaushik Bhowmick, Vimal Katiyar and Senthilkumar Sivaprakasam, “Immobilized enzymatic hydrolysis of Cassava fibrous waste for the fermentative production of optically pure D-Lactic acid” International Symposium on Advances in Sustainable Polymers (ASP-16), August 4-6, 2016, Kyoto Institute of Technology, Kyoto, Japan

28. Naresh Mohan, Senthilkumar Sivaprakasam, Development of fermentation calorimeter with improved sensitivity for bioprocess monitoring and control applications. XIX ISBC conference, June 22-24, 2016 Basel, Switzerland

2015

27. Naresh Mohan, Senthilkumar Sivaprakasam, Development of heat flux biocalorimeter as a PAT (Process analytical technology) tool to investigate rapid metabolic changes in a bioprocess system. Bioprocessing India (BPI-2015), December 17-19, Chennai, India

26. Subbi Rami Reddy Tadi, Anil M. Limaye, Senthilkumar Sivaprakasam. Potential renewable feedstocks for enhanced production of optically pure D (-) lactic acid: A comparative study. International conference on New Horizons in Biotechnology (NHBT-2015), November 22-25, 2015, NIIST Trivandrum, India

25. Subbi Rami Reddy Tadi, Srikanth Katla, Arun E.V.R, Anil M. Limaye, Senthilkumar Sivaprakasam. Technical feasibility study on production of optically pure D (-) lactic acid from Palmyra palm sugars by homolactic fermentation. Second symposium on Advances in Sustainable Polymers (APS-2015), January 21-22, 2015, IIT Guwahati, India

24. Naresh Mohan, Rengesh Balakrishnan, Senthilkumar Sivaprakasam, Optimized production of ultra-low molecular weight hyaluronic acid production by S.thermophilus employing dairy industrial waste supplement. Second symposium on Advances in Sustainable Polymers (APS-2015), January 21-22, Guwahati, India

2014

23. Subbi Rami Reddy Tadi, Srikanth Katla, Anil M. Limaye, Senthilkumar Sivaprakasam, Statistical optimization of D (-) lactic acid production in a palmyra jaggery based fermentation medium. Bioprocessing INDIA 2014: Panacea to Bioenergy, Nutrition and Healthcare, December 17-20, 2014, ICT Mumbai, India

22. Naresh Mohan, Rengesh Balakrishnan, Senthilkumar Sivaprakasam, Optimized production of ultra-low molecular weight hyaluronic acid production by S.thermophilus employing dairy industrial waste supplement. International conference on emerging trends in Biotechnology (ICETB-14), November 6-9, New Delhi, India

21. Satish Cingadi, Srikanth Katla, Senthilkumar Sivaprakasam*, Anil M Limaye. Statistical optimization of cassava fibrous waste hydrolysis by response surface methodology and use of hydrolysate based media for the production of optically pure D-Lactic acid. International conference on emerging trends in Biotechnology (ICETB-2014), November 6-9, New Delhi, India.

2013

20. Vignesh Natarajan, Srikanth Katla, Satish Cingadi, Senthilkumar Sivapraksam*, Cassava starch waste - a viable raw feedstock for the production of hyaluronic acid by Streptococcus thermophilus NCIM2904, Asian Congress on Biotechnology (ACB 2013), Dec 15-19, New Delhi, India.

19. Saurav Prasad, Srikanth Katla, Senthilkumar Sivaprakasam*, Anil M Limaye. Kinetics analysis of growth and D-lactic acid production in pH-controlled batch cultures of Lactobacillus Sp. using synthetic whey permeate medium, International Conference on Advances in Biotechnology and Patenting (ICABP -2013), February 18-21st, 2013, Trichy, Tamilnadu, India (Oral).

2012 - 2007

18. Senthilkumar S*, Marison I, Schuler MM, Biocalorimetry – A tool for Investigation of Biological Systems, Proceedings of WE-Hereaus Seminar on Biothermodynamics, 2011, Bad Honnef, Germany.

17. Schuler MM*, Senthilkumar S, Marison I, Control of the specific growth rate of yeast cells in fed-batch cultures based on calorimetric measurements, Proceedings of  WE-Hereaus Seminar on Biothermodynamics, 2011, Bad Honnef, Germany.

16. Marison I, Senthilkumar S, Schuler MM* Bioprocess monitoring and control for high cell density cultures. Proceedings of 8th European Symposium on Biochemical Engineering Science, Bologna, Italy.

15. Senthilkumar S* , Poster presentation on ‘Biocalorimetric monitoring of fed-batch bioprocess systems’, ‘Master Course on Bioprocess Engineering’ organized by European Federation of Biotechnology, Croatia. 2010, Proceedings of European Bioprocess Engineering Course.

14. Senthilkumar S*, Schuler MM and Marison I, Biocalorimetry: A Robust PAT Tool for In-line Monitoring and Control of Aerobically Grown Fed-Batch Cultures of Kluyveromyces marxianus. Proceedings of XVI International Society for Biological Calorimetry (ISBC) Conference, 2010, Santiago Compostela, Spain.

13. Schuler MM*, Senthilkumar S, and Marison I, On-line data reconciliation based on energy balances enhances the potential of biocalorimetry as a PAT process analyser. Proceedings of8th European Symposium on Biochemical Engineering Science, 2010 Bologna, Italy.

12. Freeland B, Senthilkumar S, Schuler MM* and Marison I, Application of metabolic heat flow measurements using ANNs for in-line monitoring and control of bioprocess systems. Proceedings of 8th European Symposium on Biochemical Engineering Science, 2010, Bologna, Italy.

11. Freeland B*, Senthilkumar S, Schuler MM and Marison I, ANN model for the prediction of overall heat transfer coefficient in pilot scale bioreactors for non-newtonian fluids. Proceedings of XVI International Society for Biological Calorimetry (ISBC) Conference, 2010, Santiago Compostela, Spain.

10. Senthilkumar Sivaprakasam* and Ian Marison, Progress and challenges on design of high sensitivity biocalorimeter (BioRC1) for in-line bioprocess monitoring, 13th European Congress on Biotechnology, Barcelona, Spain. New Biotechnology, Volume 25, Supplement 1, September 2009, Pages S325-S326

09. M. Izumo*, Senthilkumar S, M. Arai, K. Ishikawa, Y. Nakayama, "A comparative study on impact sensitivity of explosive materials at low temperature conditions" ISEM2008: 3rd International Symposium on Energetic Materials and their Applications, April,24-25,2008, Tokyo, Japan

08. Senthilkumar S*, Mahadevan S and Marison I, Application of Real Time Metabolic Heat Flow Measurements to Characterize Physiological behaviour of Salt-Tolerant Batch Cultures of Pseudomonas aeruginosa. Proceedings of XVI International Society for Biological Calorimetry (ISBC) Conference, 2010 Santiago Compostela, Spain.

07. Senthilkumar Sivaprakasam*, Surianarayanan Mahadevan, Swaminathan Gopalraman “Biocalorimetry- An Online tool for assessing microbial activity on industrial wastewater treatment” Southeast Asian Natural Resources and Environment Management (SANREM’06) conference, 2006, SABAH, Malaysia.

06. Senthilkumar Sivaprakasam*, Surianarayanan Mahadevan, Swaminathan Gopalraman “Application of Reaction   Calorimetry for monitoring the biological treatment of tannery saline wastewater”, International Conference on Cleaner Technologies and Environmental Management (ICCTEM’07), 2007, Pondicherry Engineering College, Pondicherry.

05. Senthilkumar Sivaprakasam*, Surianarayanan Mahadevan, Swaminathan Gopalraman “Calorimetry monitoring of biochemical reactions” International Conference for Biotechnology Engineering (ICBioE’07), University of Malaysia, Kulalampur.

04. Senthilkumar Sivaprakasam*, Surianarayanan Mahadevan, Susheela Rajakumar and Swaminathan Gopalraman “Biocalorimetric studies on biological treatment of soak liquor”, CHEMCON’03, 2003, RRL, Bhubaneswar.

03. Senthilkumar Sivaprakasam, Karunasena Ranjith*, Surianarayanan Mahadevan, Swaminathan Gopalraman “A calorimetric study on the biological activity of  P.aeruginosa cultivated in a substrate-limited growth media” SCHEMCON’06 co-organized by Anantapur University, 2006 IICHE at Anantapur.

02. Sudharshan Sekar*, Senthilkumar Sivaprakasam, Surianarayanan Mahadevan, Swaminathan Gopalraman “Isolation, Identification and Characterization of Protease from P.aeruginosa identified from tannery soak liquor”, Faculty of Engg. & Technology, Bharatidasan University, Trichy.

01. Senthilkumar Sivaprakasam*, Surianarayanan Mahadevan, Swaminathan Gopalraman “Biocalorimetric and biokinetic studies on growth of P.aeruginosa in substrate limited growth media” CHEMCON’06, 2006, GNFC, Ankleshwar, Gujarat.

Invited Lecture

04. Overcoming challenges in Legacy Bioprocess: Levaraging PAT, in AICTE-ATAL Faculty Development Program on "Fermentation Technology & Biochemical Engineering" organized by Jeppiar Engineering College, Chennai from 2nd Aug 2021 to 6th Aug 2021.

03. Energetics of Microbial Growth: Non-invasive Application of Fermentation Calorimeter in Hyaluronic acid and Human Interferon α2b Production, Biological Engineering Society 2019 Conference, 18-19 Oct 2019. IIT, Madras.

02. Identification of Critical Quality Attributes of Biopharmaceuticals, Bioprocessing INDIA 2018: Recent Advancements and Applications in Bioprocessing for Healthcare, Bioenergy and Environment, December 16-18, 2018.

01. Biotechnological valorisation of Food and Agro processing wastes for optically pure lactic production, National Conference on Valorize 2K18: Current and Future Trends in Food Waste Management and Its Valorisation, Anna University, Chennai, January 24-25, 2018.

Conference Proceedings

  • Journal Publications
  • Conference Proceedings
  • Book/Book Chapters
  • Patents

CONTACT US

BioProcess Analytical Technology (BioPAT) Laboratory, Department of Biosciences and Bioengineering, IIT Guwahati, Guwahati (Assam)-781039

Phone: +91-361-2582226 (O)

Fax No.: +91-361-2582249 (O)

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