Department of Biosciences and Bioengineering : Indian Institute of Technology Guwahati

A. B. Kunnumakkara

Professor

kunnumakkara[AT*]iitg.ac.in

Research Areas:

Role of inflammatory pathways in cancer development, Identification of novel biomarkers for cancer diagnosis and prognosis, Cancer drug discovery, Development of transgenic and gene knockout mouse models for biomedical research.

Web page: https://fac.iitg.ac.in/kunnumakkara/

Research interests: Role of inflammatory pathways in cancer development, Identification of novel biomarkers for cancer diagnosis and prognosis, Cancer drug discovery.

Major research work accomplished at IITG so far:

Developed novel drug targets for oral cancer.

Developed different formulations of drugs for better drug delivery and bioavailability.

Discovered over 40 potential anticancer drugs (preclinical studies).

Ongoing work / Future plans: Development of Novel Akt/mTOR Inhibitors for Oral cancer, Potential of natural compounds against Oral cancer, Role of different proteins in the development and progression of cancer.

Number of publications : >300 (Research articles, Reviews, and Book chapters)
Cumulative impact factor : >1000
Average impact factor : >7.0
Total number of citations : >43,000 (Goggle Scholar)
h-index : >70 (Google Scholar)
i10-index : >160 (Google Scholar)
Books published : 9 Nos

Contact

Email: kunnumakkara@iitg.ac.in

ajai78@gmail.com

Ph: 03612582231 (Office)/ 3220 (Lab)

7896005326 (Mobile)

Ph.D : Biochemistry, Amala Cancer Research Center, Thrissur, University of Calicut, Kerala, India, 2006.
M.Sc : Botany, ST. Thomas’ College, Thrissur, University of Calicut, Kerala, India, 2001.
B.Sc : Botany, Sree Narayana College, Nattika, Thrissur, University of Calicut, Kerala, India, 1999.

09/2019- Present : Professor, Department of Biosciences and Bioengineering, IIT Guwahati, Assam, India.
04/2015 – 08/2019 : Associate professor, Department of Biosciences and Bioengineering, IIT Guwahati, Assam, India.
08/2012 - 04/2015 : Assistant professor, Department of Biosciences and Bioengineering, IIT Guwahati, Assam, India.
07/2010 - 07/2012 : Research Fellow (NIH Scientist), National Cancer Institute (NCI/NIH), Bethesda, Maryland, USA.
10/2008 - 07/2010 : Postdoctoral Fellow, National Cancer Institute (NCI/NIH), Bethesda, Maryland, USA.
08/2006 - 10/2008 : Postdoctoral Fellow, M.D. Anderson Cancer Center, Houston, Texas, USA.
07/2005 - 08/2006 : Research Intern, M.D. Anderson Cancer Center, Houston, Texas, USA.

Courses taught:

Animal Cell Biotechnology
Gene Therapy
Stem Cells, Cancer and Therapy
Applied Biology and Bio-engineering Lab
Animal Models in Biomedical Research
Modern Biology
Biochemistry
Genetics
Frontiers in Biotechnology

Journals

1. Khwairakpam AD, Banik K, Girisa S, Shabnam B, Shakibaei M, Fan L, Arfuso F, Monisha J, Wang H, Mao X, Sethi G, Kunnumakkara AB. "The vital role of ATP citrate lyase in chronic diseases.", J Mol Med (Berl). . DOI.doi: 10.1007/s00109-019-01863-0, Vol.98, 1, P.P 71-95 , (2020)

2. Banik K, Ranaware AM, Harsha C, Nitesh T, Girisa S, Deshpande V, Fan L, Nalawade SP, Sethi G, Kunnumakkara AB. "Piceatannol: A natural stilbene for the prevention and treatment of cancer.", Pharmacol Res. . DOI.10.1016/j.phrs.2020.104635., Vol.153, 104635, P.P - , (2020)

3. Khatoon E, Banik K, Harsha C, Sailo BL, Thakur KK, Khwairakpam AD, Vikkurthi R, Devi TB, Gupta SC, Kunnumakkara AB "Phytochemicals in cancer cell chemosensitization: Current knowledge and future perspectives", Seminars in Cancer Biology. DOI.10.1016/j.semcancer.2020.06.014, Vol., , P.P - , (2020)

4. Bordoloi D, Banik K, Padmavathi G, Vikkurthi R, Harsha C, Roy NK, Singh AK, Monisha J, Wang H, Kumar AP, Kunnumakkara AB. "TIPE2 Induced the Proliferation, Survival, and Migration of Lung Cancer Cells Through Modulation of Akt/mTOR/NF-?B Signaling Cascade.", Biomolecules. . DOI.10.3390/biom9120836, Vol.12, 9, P.P pii: E836.- , (2019)

5. Roy NK, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar NS, Singh AK, Bordoloi D, Baruah MN, Ahmed GN, Longkumar I, Arfuso F, Kumar AP, Kunnumakkara AB. "Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.", Biomolecules. . DOI.10.3390/biom9070253, Vol.7, 9, P.P pii: E253.- , (2019)