Professional Experience
Research Group

1. Host-pathogen interaction of infectious diseases.


2. Gene expression analysis of spirochetes: Leptospira interrrogans and Borrelia burgdorferi.


3. Development of diagnostics and vaccine against OMP's of Leptospira interrogans and Borrelia


4. Vector-borne diseases of zoonotic importance.

1. B.V.Sc. & A.H. (1999-2004): Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, College of Veterinary Sciences, Uttaranchal, India.


2. M.V.Sc. (2004- 2006): In Veterinary Public Health (VPH), Indian Veterinary Research Institute (IVRI), Izatnagar, Bareilly, UP, India.


3. Ph.D. (2006-2010): In Veterinary Medical Sciences (VMSC), University of Maryland (UMD), College Park, USA.

1.  Junior Research Fellow (Aug 2004- July 2006):  Division of Veterinary Public Health (VPH), Indian Veterinary Research Institute (IVRI), Izatnagar, Bareilly, UP, India

2. Research Assistant (Aug 2006- Dec 2010): Veterinary Medical Sciences, University of Maryland, College Park, USA.

3. Postdoctoral fellow/ Research Associate (Jan 2011- May 2012): Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, USA.

4. Assistant Professor (June 2012-  Jan 2017): Department of Biosciences and Bioengineering, IIT Guwahati. 

5. Associate Professor ( Jan 2017- Sept 2021): Department of Biosciences and Bioengineering, IIT Guwahati.

6Professor (Sept 2021- present): Department of Biosciences and Bioengineering, IIT Guwahati.



1. Molecular Biology and Genetic Engineering BT 208 (JAN-MAY 2013)

2. Microbial Biotechnology BT 608 (JAN-MAY 2014, JULY-NOV 2018) 

3. Immunology BT 303 (JULY-NOV 2014, 2015, 2016 , 2020 and 2021)

4. Modern Biology BT 101 (JAN-MAY 2015, 2016 & 2017)

5. Molecular Biotechnology Laboratory BT 380 (JULY-NOV 2017)

6. Microbiology BT 202 (JAN-MAY 2018 & 2019)

7. Human Biology and Diseases BT 633 (JULY-NOV 2018; 2019; JAN-MAY 2021)

8. Molecular Biotechnology (MINOR) BT 202M ((JAN-MAY 2019)

9. Applied Biology and Bioengineering Laboratory BT 520 (Jan-May 2020)

10. Seminar Course BT 300 (Jan-May 2020)



1. Dhara A, Hussain M S, Kanaujia S P, Kumar M "Acyldepsipeptide activated ClpP1P2 macromolecule of Leptospira, an ideal Achilles’ heel to hamper the cell survival and deregulate ClpP proteolytic activity", Research in Microbiology. DOI.10.1016/j.resmic.2021.103797, Vol., , P.P - , (2021)

2. Harshini S P, Ghosh K K, Kumari R R, Kumar P, Kumar M "Evaluation of sporozoite and macroschizont antigen (Spm2) of Theileria annulata for its diagnostic potential", Ticks and Tick-borne Diseases. DOI., Vol.12, 4, P.P - , (2021)

3. Prakash A, Kumar M "Characterizing the transcripts of Leptospira CRISPR I-B array and its processing with endoribonuclease LinCas6", International Journal of Biological Macromolecules. DOI.10.1016/j.ijbiomac.2021.04.066, Vol.182, , P.P 785-795 , (2021)

4. Dixit B, Anand V, Hussain M S, Kumar M "The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrate versatile nuclease activity", Current Research in Microbial Sciences. DOI., Vol.2, 100040, P.P - , (2021)

5. Hota S, Hussain M S, Kumar M "ErpY-like lipoprotein of Leptospira outsmart host complement regulation by acquiring complement regulators, activating alternate pathway, and intervening membrane attack complex", bioRxiv. DOI. , Vol., , P.P - , (2021)

Conference Publication

1. Md. Saddam Hussain, Manish Kumar "The burgeoning CRISPR-Cas applications", Biotechnological Approaches in Animal Research and Disease Diagnosis. Vol., , P.P - , (2021)

2. Md. Saddam Hussain, Manish Kumar "Leptospira Cas8b protein: a genetic fusion of large and small subunit of CRISPR-Cas type I-B Cascade complex", Emerging areas in Biosciences and Biomedical Technologies-2 (eBBT-2). Vol., , P.P 46-46 , (2020)

3. Madhurima Choudhury, Manish Kumar "The novel role of trigger factor in stimulating caseinolytic serine protease activity of Leptospira", Emerging Areas in Biosciences and Biomedical Technologies-2. Vol., , P.P 47-47 , (2020)

4. Vineet Anand and Manish Kumar "Biochemical characterization of a core Cas protein of CRISPR-Cas subtype-IC in Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130", Challenges and Threats of Microbes to Animals and Humans. Vol., , P.P - , (2020)

5. Saha G, Khamar B.M, Kumar M, Dubey V.K "Unraveling the role of BLIMP-1 induction during Leishmania donovani infection as a novel escape mechanism", 17th International conference of Immunology, Oct 19-23, 2019 Beijing China. Vol.49, S3, P.P 1174-1175 , (2019)

View All Publications

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