Bose Biplab

Associate Professor

Research Areas:

Systems Biology, Dynamical Systems, Mathematical Biology, Complex System, Cell Signaling

Web page:


1. Vimalathithan Devaraj, Biplab Bose "DEBay: A computational tool for deconvolution of quantitative PCR data for estimation of cell type-specific gene expression in a mixed population", Heliyon, DOI., Vol.6, 7, P.P e04489- , (2020)

2. Vimalathithan Devaraj, Biplab Bose "The Mathematics of Phenotypic State Transition: Paths and Potential", Journal of the Indian Institute of Science, DOI.10.1007/s41745-020-00173-6, Vol.100, 3, P.P 451-464 , (2020)

3. Agarwal M, Mondal T, Bose B "Peptides derived from a short stretch of diphtheria toxin bind to heparin-binding epidermal growth factor-like growth factor", Toxicon, DOI., Vol.169, , P.P 109-116 , (2019)

4. Chandrasekaran K, Bose B "Percolation in a reduced equilibrium model of planar cell polarity", Physical Review E, DOI., Vol.100, , P.P 032408- , (2019)

5. Devaraj V, Bose B "Morphological State Transition Dynamics in EGF-induced Epithelial to Mesenchymal Transition", Journal of clinical medicine , DOI., Vol.8, 7, P.P E911.- , (2019)

6. Agarwal M, Sahoo AK, Bose B. "Receptor-Mediated Enhanced Cellular Delivery of Nanoparticles Using Recombinant Receptor-Binding Domain of Diphtheria Toxin. ", Molecular Pharmacology, DOI., Vol.14, 1, P.P 23-30 , (2017)

7. Loying P, Manhas J, Sen S, Bose B. "Autoregulation and Heterogeneity in Expression of Human Cripto-1", Plos one, DOI., Vol.10, 2, P.P 1-17 , (2015)

8. Thakur R, Kumar A, Bose B, Panda D, Saikia D, Chattopadhyay P, Mukherjee AK. "A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa", Biochimie, DOI., Vol.105, , P.P 149-158 , (2014)

9. Kumar A, Das G, Bose B. "Recombinant Receptor-binding Domain of Diphtheria Toxin Increases Potency of Curcumin by Enhancing Cellular Uptake", Molecular Pharmacology, DOI., Vol.11, 1, P.P 208-217 , (2013)

10. Bose B. "Systems biology: A biologist's viewpoint.", Progress in Biophysics and molecular biology, DOI., Vol.113, 1, P.P 358-368 , (2013)

11. Das AB, Loying P, Bose B. "Human recombinant Cripto-1 increases doubling time and reduces proliferation of HeLa cells independent of pro-proliferation pathways.", Cancer Letters, DOI., Vol.318, 2, P.P 189-198 , (2012)

12. Bose B, Khanna N., Acharya S.K., Sinha S. " Generation and characterization of a single gene mouse-human chimeric antibody against hepatitis B surface antigen.", Journal of Gastroenterology and Hepatology, DOI., Vol.21, 9, P.P 1439-1447 , (2006)

13. Bose B, Khanna N., Acharya S.K., Sinha S "Generation and characterization of a chimeric antibody against Hepatitis B surface antigen. ", Biotechnology and Applied biochemistry, DOI., Vol.43, 2, P.P 93-101 , (2006)

14. Bose B, Khanna N., Acharya S.K., Sinha S "A high affinity mouse-human chimeric Fab against Hepatitis B surface antigen.", World journal of gastroenterology, DOI., Vol.11, 48, P.P 7569-7578 , (2005)

15. Bose B, Sinha S. "Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen driven affinity selection.", Immunology, DOI., Vol.116, 2, P.P 172-183 , (2005)

16. Bose B, Chugh D.A., Kala M., Acharya S.K., Khanna N., Sinha S. "Characterization and molecular modeling of a highly stable anti-Hepatitis B surface antigen scFv", Molecular Immunology, DOI., Vol.40, 9, P.P 617-631 , (2003)

Conference Publication

1. Prasanna N.A., Bose B. "Molecular Modeling and structural analysis of NS3 Helicase of West Nile Virus. ", Indo-French Bioinformatics Meeting (IFBM2006), National Center for Biological Sciences, Bangalore. Vol., , P.P - , (2006)

2. Das A. B., Bose B "Heterologous Expression of Human Oncofetal Protein Cripto-1", 77th Annual meeting of Society Of Biological Chemists , IIT Madras, Chennai,. Vol., , P.P - , (2008)

3. M. S. Sudarsan, Dwivedi G., Bose B "B Cell Receptor Dynamics: Effect Of Ligand Valency.", Integrating Physics, Chemistry, Mathematics and Biology to Understand Living Systems (IPCMB 2008), Bose Institute, Kolkata. Vol., , P.P - , (2008)

4. Batra S, Bose B. "Effect Of Ligand Mediated Cross-Linking On Lateral Diffusion Of Cell Surface Receptors.", International Conference on Physics Biology Interface ,Saha Institute of nuclear physics kolkata. Vol., , P.P - , (2009)

5. Mehta T, Bose B. "FlowPy: a python tool for extraction of flow cytometry data.", The Eighth Asia Pacific Bioinformatics Conference , Bangalore. Vol., , P.P - , (2010)

6. Kumar A, Bose B "Truncated Diphtheria Toxin as a Novel Therapeutic Agent, Carcinogensis , New Delhi, ", . Vol., , P.P - , (2012)

7. Loying P., Chaturvedi R., Bose B. "Design Principle of the Transcriptional Circuit of Human Cripto-1", 3rd International Conference on Stem Cells and Cancer (ICSCC- 2012), New Delhi. Vol., , P.P - , (2012)

8. Loying P., Agarwal M., Bose B. "Involvement of Mitogenic Pathways in Expression of Human Cripto-1", 4th International Conference on Stem Cells and Cancer , Mumbai. Vol., , P.P - , (2013)

9. Loying P., Agarwal M., Bose B. "Transcriptional Circuit of Human Cripto-1: Exploring Expression Heterogeneity. ", Cell Signaling in Metabolism, Inflammation and Cancer, Cold Spring Harbor Asia Conferences, China. Vol., , P.P - , (2013)

10. Loying P., Manhas J., Sen S., Bose B. "Cellular Heterogeneity in Expression of an Oncofetal Protein", 83rd Annual Meeting of Society Of Biological Chemists (India) Bhubaneshwar. Vol., , P.P - , (2014)

11. Loying P., Bose B. "Exploring Heterogeneity in Expression of Human Cripto-1.", International Conference on Disease Biology and Therapeutics, Guwahati. Vol., , P.P - , (2014)

12. Bose B "All Cells are Equal, But Some are More Equal Than Others. ", National Seminar on Recent Advances in Biotechnological Research in North East India: Challenges and Prospects, Tezpur University. Vol., , P.P - , (2014)

13. Dutta P., Devaraj V., Bose B. "Characterization of a Negative Feedback in PI3K/Akt pathway", International symposium on Systems, Synthetic and Chemical Biology, Bose Institute Kolkata.. Vol., , P.P - , (2017)

14. Devaraj V, Bose B "Understanding the Cellular State Transition in Epithelial to Mesenchymal Transition", 1st IBSE International Symposium, IIT Madras. Vol., , P.P - , (2018)

15. Devaraj V, Dutta P, Bose B "Signal Discrimination through a Negative Feedback", RTG Big Data Research Summer School, Allahabad University. Vol., , P.P - , (2019)


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