Patents

 

4. Indian Patent Application (complete specifications),  filed on 14.12.2017, Title: “A NOVEL COUPLING REAGENT FOR ESTERIFICATION, THIOESTERIFICATION, AMIDATION AND PEPTIDE SYNTHESIS” . Application No. 201731045011, Inventors: Dr. Bhubaneswar Mandal, Ms. Jyoti Chandra, Mr. Srinivasa Rao Manne and Mr. Sandip Mondal

 

3. Indian patent application (complete specifications), filed on the 9th May, 2017; Title: “A METHOD FOR PREPARTION OF SULPHONATES OF ALCOHOL, OXIME-O-SULPHONATES AND THEIR DERIVATIVES”; Application No. 201731016281; Inventors: Dr. Bhubaneswar Mandal and Ms. Jyoti Chandra.

 

2. Indian patent application (complete specifications), filed on the 26th May, 2016; Title: TITLE: “β-SHEET BREAKER PEPTIDES FOR DRUG DESIGN AGAINST DIABETES TYPE-2”; Application No. 201631018104; Inventors: Dr. Bhubaneswar Mandal and Mr. Ashim Paul.

 

1. Indian patent application (complete specifications), filed on the 17th September, 2015; Title: Beta Sheet Breaker Peptides for Anti-Alzheimer's Drug Design; Application No. E-2/1727/2015/KOL; Inventors: Dr. Bhubaneswar Mandal and Mr. Ashim Paul. A provisional application was filed on the 26th September, 2014; Application No. 997/KOL/2014.

 

 

 

 

 

Publications

 

  46. Jyoti Chandra, Srinivasa Rao Manne, Sandip Mondal, Bhubaneswar Mandal*, "(E)-Ethyl-2-cyano-2-(((2, 4, 6-trichlorobenzoyl) oxy) imino) acetate: A Modified Yamaguchi Reagent for Enantioselective Esterification, Thioesterification, Amidation, and Peptide Synthesis", ACS Omega, 2018, 3(6), 6120-6133. 

DOI: 10.1021/acsomega.8b00732

  45. Rajat Subhra Giri, Bhubaneswar Mandal*, "Boc-Val-Val-OMe (Aβ39-40) and Boc-Ile-Ala-OMe (Aβ41-42) crystallize in parallel β-sheet arrangement but generate different morphology", CrystEngComm, 2018, 20, 4441-4448, DOI: 10.1039/c8ce00097
   

44. Srinivasa Rao Manne, Jyoti Chandra, Rajat Subhra Giri, Tapasi Kalita, and Bhubaneswar Mandal*, "Synthesis of -Amino Alcohols Using Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY)", ChemistrySelect, 2018, 3, 992–996, DOI: 10.1002/slct.201702713.

  43. Ashim Paul, Sourav kumar, Sourav Kalita, Anup Kumar Ghosh, Amal Chandra Mondal* and Bhubaneswar Mandal*, "A Peptide Based Pro-Drug Disrupts Alzheimer's Amyloid into Non-Toxic Species and Reduces Aβ Induced Toxicity in vitro", International Journal of Peptide Research and Therapeutics, 2018, 24(1), 201–211. DOI: 10.1007/s10989-017-9602-8.
   

42. Rajat Subhra Giri, Srinivasa Rao Manne, Gobinda Dolai, Ashim Paul, Tapasi Kalita, Bhubaneswar Mandal*, “FeCl3-Mediated Side Chain Modification of Aspartic Acid-and Glutamic Acid-Containing Peptides on a Solid Support” ACS Omega, 2017, 2, 6586−6597, DOI: 10.1021/acsomega.7b01143

   

41. Jyoti Chandra, Rohit Chaudhuri, Srinivasa Rao Manne, Sandip Mondal, Bhubaneswar Mandal*, “Direct Synthesis of Sulphonates of Alcohol, Oxyma-O-sulphonates and Oxime-O-sulphonates under Microwave Irradiation”, ChemistrySelect, 2017, 2, 8471-8477, DOI: 10.1002/slct.201701554

   

40. Sourav Kumar, Ashim Paul, Awanish Kumar, Somoday Hazra, Anup Kumar Ghosh, Bhubaneswar Mandal and Amal Chandra Mondal*, "A Peptide Based Pro-Drug Ameliorates Amyloid-β Induced Neuronal Apoptosis in in vitro SH-SY5Y cells", Current Alzheimer Research, 2017, 14(12), 1293-1304.  DOI: 10.2174/1567205014666170713153414

   

39. Saumya Prasad, Imon Mandal, Shubham Singh, Ashim Paul, Bhubaneswar Mandal, Ravindra Venkatramani, Rajaram Swaminathan, “Near UV-Visible Electronic Absorption Originating from Charged Amino Acids in a Monomeric Protein”, Chem. Sci., 2017,8, 5416-5433 , DOI: 10.1039/C7SC00880E, Edge Article

 

38. Ashim Paul, Sourav Kalita,  Sujan Kalita, Piruthivi Sukumar and Bhubaneswar Mandal*, "Disaggregation of Amylin Aggregate by Novel Conformationally Restricted Aminobenzoic Acid containing α/β and α/γ Hybrid Peptidomimetics", Scientific Reports (Nature Publishing  Group) :7, 40095; doi: 10.1038/srep40095 (2017). (link)

 

 

 

 

37. Sourav kumar, Ashim Paul, Sourav Kalita, Anup Kumar Ghosh, Amal Chandra Mondal* and Bhubaneswar Mandal*, "Protective effects of β-sheet breaker α/β hybrid peptide against Amyloid β induced neuronal apoptosis in vitro", Chemical Biology and Drug Design, 2017 Jun;89(6):888-900. doi: 10.1111/cbdd.12912.  (link)

 

36.  Srinivasa Rao Manne, Kishore Thalluri, Rajat Subhra Giri, Jyoti Chandra and
Bhubaneswar Mandal*, "Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma): An Efficient Reagent for the Racemization Free Synthesis of Ureas, Carbamates and Thiocarbamates via Lossen Rearrangement" Advanced Synthesis and Catalysis, 2017, 359, (1), 168–176. http://onlinelibrary.wiley.com/doi/10.1002/adsc.201600661/abstract. (link)

 

 

35. Bhanita Sharma, Sourav Kalita, Ashim Paul, Bhubaneswar Mandal and Sandip Paul*, "The role of caffeine as an inhibitor in the aggregation of amyloid forming peptides: a unified molecular dynamics simulation and experimental study" RSC Advances, 2016, 6, 78548–78558.(link)

 

34. Lian Gelis*, Nikolina Jovancevic, Sophie Veitinger, Bhubaneswar Mandal, Hans-Dieter Arndt, Eva M. Neuhaus, and Hanns Hatt, "Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes", The Journal of Biological ChemistryTHE JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (34), 17772–17786. Published on May 18, 2016, The latest version is at http://www.jbc.org/cgi/doi/10.1074/jbc.M116.734517. (link)

33.  Dharm Dev, Jyoti Chandra, Nani Babu Palakurthy, Kishore Thalluri, Tapasi Kalita and Bhubaneswar Mandal*, "Benzoxazole and Benzothiazole Synthesis from Carboxylic Acid in Solution and on Resin by Ethyl 2-cyano-2-(2-nitro-benzenesulfonyloxyimino) acetate and para-Toluenesulfonic Acid", Asian Journal of Organic Chemistry, DOI: 10.1002/ajoc.201500527, published online on 19/02/2016. Volume 5, Issue 5, pages 663–675, May 2016.(link)

                                                              (Invited for a cover page)

 

   

32. Saumya Prasad, Imon Mandal, Ashim Paul, Bhubaneswar Mandal, Ravindra Venkatramani, Rajaram Swaminathan, “Investigation of Novel Spectroscopic Features in the Near Ultraviolet Region Arising from Non-Aromatic Amino Acids in Peptides and Proteins”, BIOPHYSICAL JOURNAL, 2016, 110 (3), 489A-489A.

 

31. Ashim Paul, Bhanita Sharma, Tanmay Mondal, Kishore Thalluri, Sandip Paul and Bhubaneswar Mandal*, "Amyloid β Derived Switch-Peptides as a Tool for Investigation of Early Events of Aggregation: A Combined Experimental and Theoretical Approach",  Med. Chem. Commun., 2016, 7, 311-316. (link)

 (Highlighted in a retrospective collection entitled, "
Neurodegenerative diseases", by RSC)

 

30. Bhubaneswar Mandal*, "Novel and innovative strategies for peptide based drug design against Alzheimer's disease", J Pharma Care Health Sys, 2015, 2 (5), 34.

 

 

29.  Srinivasa Rao Manne, Kishore Thalluri, Rajat Subhra Giri, Ashim Paul, and Bhubaneswar Mandal*, "Racemization free longer N-terminal peptide hydroxamate synthesis on solid support using ethyl 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetate" Tetrahedron Letters, 2015, 56 (44), 6108-6111.(link)

 

28.  Kirtikumar B. Jadhav, Roman J. Lichtenecker, Anke Bullach, Bhubaneswar Mandal, and Hans-Dieter Arndt*, "Dynamic combinatorial enrichment of polyconformational D-/L-peptide dimers" Chemistry - A European Journal, 2015, 21 (15), 5898–5908. Highlighted as cover page and Hot Paper. (link)

27.  Ashim Paul, Krishna Chaitanya Nadimpally, Tanmay Mondal, Kishore Thalluri, and Bhubaneswar Mandal*, "Inhibition of Alzheimer’s Amyloid-β Peptide Aggregation and its Disruption by a Conformationally Restricted α/β Hybrid Peptide" Chemical Communications, 2015, 51, 2245-2248. (link)

(Highlighted as cover page)

26. Kishore Thalluri, Ashim Paul, Srinivasa Rao Manne, Dharm Dev, and Bhubaneswar Mandal*, "Microwave Assisted Chemoselective Organocatalytic Peptide Alcohol Synthesis from C-terminal Amide" RSC Advances, 2014, 4 (88), 47841 - 47847. (link)

 

  25.    (Book Chapter) Kishore Thalluri, Dharm Dev, Nani Babu Palakurthy, Srinivasa Rao Manne, Jyoti Chandra and Bhubaneswar Mandal*, "The Coupling Reagents the World in Need Indeed", in Proceedings of International Conference on New Dimensions in Chemistry & Chemical Technologies ‒ Applications in Pharma Industry, NDCT-2014, 23th-25th June, 2014, JNTU Hyderabad.  Prof. K. Mukkanti (Editor-in-Chief), Spectrum Publications, Hyderabad-500038, A. P. India. (ISBN 978-93-82829-90-4) 2014, p 348-351.

 

24.  Dharm Dev, Nani Babu Palakurthy, Kishore Thalluri, Jyoti Chandra, and Bhubaneswar Mandal*, "Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): A Recyclable Coupling Reagent for Racemization free Synthesis of Peptide, Amide, Hydroxamate and Ester" The Journal of Organic Chemistry, 2014, 79 (12), 5420–5431. (link)

(Recently, the reported reagent has got  CAS No. 1441409-96-6.

Highlighted in ChemInform, Volume 45,  Issue 50, December 16, 2014, DOI: 10.1002/chin.201450187.

Highlighted in Organic Chemistry Portal as one of "the most significant
current developments in organic synthesis". http://www.organic-chemistry.org/Highlights/2015/09March.shtm
)

 

23.    Kishore Thalluri, Srinivasa Rao Manne, Dharm Dev and Bhubaneswar Mandal*, "Ethyl 2-cyano-2-(4-nitrophenylsulfonyloxyimino)acetate (4-NBsOXY) Mediated Lossen Rearragement: Single Pot Racemization free Synthesis of Hydroxamic Acids and Ureas from Carboxylic Acids" The Journal of Organic Chemistry,  2014, 79 (9),  3765–3775. (link)

(Recently, the reported reagent has got  CAS No. 1441409-91-1.

Highlighted in ChemInform, Volume 45, Issue 38, 4 SEP 2014, DOI: 10.1002/chin.201438085.

Highlighted in Organic Chemistry Portal as one of "the most significant
current developments in organic synthesis". http://www.organic-chemistry.org/Highlights/2015/16March.shtm
)

 

22.    Krishna Chaitanya Nadimpally, Ashim Paul and Bhubaneswar Mandal*, "Reversal of aggregation using β breaker dipeptide containing peptides: Application to Aβ(1-40) self assembly and its inhibition" ACS Chemical Neuroscience,  2014, 5 (5), 400–408. (link)

(Highlighted in PUBFACTS, http://www.pubfacts.com/detail/24661180/Reversal-of-aggregation-using-%CE%B2-breaker-dipeptide-containing-peptides:-Application-to-A%CE%B21-40-self-)

 

21.    Nani Babu Palakurthy, Dharm Dev, Sonali Paikaray, Susmitnarayan Chaudhury, and Bhubaneswar Mandal*, "Synthesis of O-Benzyl hydroxamates Employing the Sulfonate Esters of N-Hydroxybenzotriazole" RSC Advances, 2014, 4 (16), 7952 - 7958. (link)

(Highlighted in ChemInform, Volume 45,  Issue 46, November 18, 2014, DOI: 10.1002/chin.201446088)

 

20.    Abhijit Saha, Krishna Chaitanya Nadimpally, Ashim Paul, Sourav Kalita and Bhubaneswar Mandal*, "Phenolic ester mediated oligopeptide synthesis promoted by HOBt" Protein and Peptide Letters, 2014, 21 (2), 188-193. (link)

19.    Nadimpally Krishna Chaitanya, Ashim Paul, Abhijit Saha and Bhubaneswar Mandal*, "Modulation of Aggregation Propensity of Aβ38 by Site Specific Multiple Proline Substitution" International Journal of Peptide Research and Therapeutics, ,19, 365-371. (link)

 

(Highlighted in "Sciences Indexed Since 1998" http://scienceindex.com/stories/3285684/Modulation_of_Aggregation_Propensity _of_A38_by_Site_Specific_Multiple_Proline_Substitution.html)

18.    Dharm Dev, Nani Babu Palakurthy, Nitesh Kumar and Bhubaneswar Mandal*, "An unexpected involvement of ethyl-2-cyano-2-(hydroxyimino) acetate cleaved product in the promotion of the synthesis of nitriles from aldoximes: A mechanistic perception" Tetrahedron Lett., 2013, 4397-4400. (link)

(Highlighted in ChemInform, Volume 44, Issue 47, November 19, 2013. DOI: 10.1002/chin.201347061.

Highlighted in VerticalNews, as “New Nitriles Has Been Reported by Investigators at Indian Institute of Technology” on SEP 13, 2013.
http://chemical-and-chemistry.verticalnews.com/articles/10215040.html)

 

17.    Nani Babu Palakurthy, Dharm Dev, Shubhasmin Rana, Krishna Chaitanya Nadimpally and Bhubaneswar Mandal*, "Sulfonamide Synthesis via Oxyma-O-sulfonates – Compatibility to Acid Sensitive Groups and Solid-Phase Peptide Synthesis" Eur. J. Org. Chem., 2013, 2627–2633. (link)

(Highlighted in ChemInform, Volume 44, Issue 40, October 1, 2013. DOI: 10.1002/chin.201340075.

Highlighted in VerticalNews, as “Findings on Organic Chemistry Reported by Investigators at Indian Institute of Technology” on June 14th, 2013. http://www.verticalnews.com/newsletters/Chemicals-and-Chemistry/2013-06-14/64489CH.html)

 

16.    Kishore Thalluri, Krishna Chaitanya Nadimpally, Maharishi Parasar Chakravarty, Ashim Paul and Bhubaneswar Mandal*; "Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-Cyanoacetate (Boc-Oxyma) as Coupling Reagent for Racemization free Esterification, Thioesterification, Amidation and Peptide Synthesis"  Advanced Synthesis and Catalysis, 2013, 355, 448-462.  (link)

(Recently, the reported reagent has got  CAS No. 1426821-11-5 .

Highlighted in ChemInform, Volume 44, Issue 30. DOI: 10.1002/chin.201330049.)
 

15.    Kishore Thalluri, Krishna Chaitanya Nadimpally, Ashim Paul and Bhubaneswar Mandal*; "Waste reduction in amide synthesis by a continuous method based on recycling of the reaction mixture" RSC Advances, 2012, 2, 6838–6845. (link)

14.  Nani Babu Palakurthy and Bhubaneswar Mandal*; "Sulfonamide synthesis using N-hydroxybenzotriazole sulfonate: an alternative to pentafluorophenyl (PFP) and trichlorophenyl (TCP) esters of sulfonic acids" Tetrahedron Lett. 2011, 52, 7132-7134. (link)

13.   Krishna Chaitanya Nadimpally, Kishore Thalluri, Nani Babu Palakurthy, Abhijit Saha and Bhubaneswar Mandal*; "Catalyst and solvent free amidation of inactiveesters of N-protected amino acids" Tetrahedron Lett. 2011, 52, 2579-2582. (link)

 

Before joining IITG

12.  Marie-Stephanie Camus, Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar Mandal, Adrian W. Schmid, Gabriele Tuchscherer, Manfred Mutter* and Hilal A. Lashuel*; "Switch-Peptides: Design and characterization of controllable super-amyloid-forming host-guest peptides as tools for identifying anti-amyloid agents" ChemBioChem, 2008, 9, 2104-2112. (link)

11.    Manfred Mutter*, Jeremy Berard, Marie-Stephanie Camus, Gabriele Tuchscherer, Arunan Chandravarkar, Bhubaneswar Mandal, Sonia Dos Santos, Lydiane Saucede, Eric Grouzmann, Karine Murat, Richard Mimna; "Switch-peptides as folding precursors in amyloid fibrillogenesis" Peptide science, 2006, 43 (LCBP-ARTICLE-2007-003), 30-31. (link)

10. (Book Chapter) Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar mandal, Karine Murat, Lydiane Saucede, Marie-Stephanie Camus, Gabriele Tuchscherer and Manfred Mutter*; "Switch on Amyloid beta Peptide Self-Assembly by Enzyme-Triggered Acyl Migration", in Understanding Biology using Peptides, Blondelle Sylvie E. (Editor), Springer, (ISBN 978-0-387-26575) 2006, chapter 13, p 56-58.

9.    Lydiane Saucede, Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar Mandal, Richard Mimna, Karine Murat, Marie-Stephanie Camus, Jeremy Berard, Eric Grouzmann, Marc Adrian, Jacques Dubochet, John Lopez, Hilal Lashuel, Gabriele Tuchscherer and Manfred Mutter*; "Switch-peptides: From conformational studies to Alzheimer’s disease" Chimia. 2006, 60, 199-202. (link)

8.    Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar mandal, Richard Mimna. Karine Murat, Marie-Stephanie Camus, Lydiane Saucede, Gabriele truscherer and manfred mutter*; " Switch on amyloid beta peptide self-assembly by enzyme triggered acyl migration" Peptide Science, 2005, 80, 568-568. (link)

7.    Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar mandal, Richard Mimna. Karine Murat, Lydiane Saucede, Patrica tella, Gabriele Truscherer and Manfred mutter*; " Switch-peptide: Controlling self assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migration" J. Am. chem. Soc. 2005, 127, 11888-11889. (link)

6. Arunan Chandravarkar, Bhubaneswar mandal, Sonia Dos Santos, Luc Patiny, Gabriele Tuchscherer, Manfred mutter*; "Switch-peptides: ISN induction of conformational transitions relevant in degenerative diseases" J. Pep. Sc. 2004, 10, 100-100. (link)

5.   Manfred Mutter*, Arunan Chandravarkar, Christine Boyat, John Lopez, Sonia Dos Santos, Bhubaneswar Mandal, Richard Mimna, Karine Murat, Luc Patiny, Lydiane Saucede and Gabriele Tuchscherer; "Switch-peptides in statu nascendi: induction of conformational transitions relevant to degenerative diseases" Angew. Chem. Int. Ed. 2004, 43, 4172-4178. (link)

"Switch-Peptide in statu nascendi: Induktion von Konformationsübergängen und deren Bedeutung in degenerativen Erkrankungen" Angewandte Chemie 2004, 116 (32), 4267-4273.

4.    Arunan Chandravarkar, Bhubaneswar Mandal, Sonia Dos Santos, Gabriele Tuchscherer and Manfred Mutter*; "Switch-peptides: ISN-nucleation and disruption of secondary structures relevant in degenerative diseases." Peptides, 2004, 52. (link)

3. Damiano Banfi, Bhubaneswar Mandal, Manfred Mutter* and Luc Patiny; "Evolutionary principles for generating protein mimetics: Directed assembly of peptide loops on topological templates" Acta Biochim. Pol., 2001, 48, 1105-1107. (link)

2.   Surajit Sinha, Bhubaneswar Mandal and Srinivasan Chandrasekaran*; "Synthesis of ethyl arylacetates by means of Friedel-Crafts reactions of aromatic compounds with ethyl -chloro--(ethylthio)acetate catalyzed by ytterbium triflate" Tetrahedron Lett. 2000, 41, 9109-9112. (link)

(Highlighted in ChemInform, Volume 32, Issue 8, February 20, 2001. Article first published online: 30 MAY 2010; DOI: 10.1002/chin.200108122.)

1.   Surajit Sinha, Bhubaneswar Mandal and Srinivasan Chandrasekaran*; "Selective para metalation of unprotected 3-methoxy and 3,5-dimethoxy benzoic acids with n-butyllithium-potassium tert-butoxide (LIC-KOR): synthesis of 3,5-dimethoxy-4-methyl benzoic acid" Tetrahedron Lett. 2000, 41, 3157-3160. (link)

(Highlighted in ChemInform, Volume 31, Issue 36, September 5, 2000. Article first published online: 3 JUN 2010; DOI: 10.1002/chin.200036085.)

 

 

Abstracts published in conference proceedings:

 

38. Jyoti Chandra and Bhubaneswar Mandal* Direct Synthesis of Oxyma-O-sulphonates, Sulphonates of Alcohols and Oxime-O-sulphonates under Microwave Irradiation and its Application in Relevant Organic Transformation, XIII J-NOST Conference for Research Scholars (J-NOST-2017), 9th November, 2017, Department of Chemistry, Banaras Hindu University, Varanasi, PP-14 (Poster).

37. Rajat Subhra Giri and Bhubaneswar Mandal* Lewis Acid based Side Chain Modification of Aspartic Acid and Glutamic Acid during Solid Phase Peptide Synthesis, 20th CRSI National Symposium in Chemistry, Department of Chemistry, 3rd Feb 2017, Gauhati University, Page 221 (PP-296).

36. Jyoti Chandra, Dharm Dev and Bhubaneswar Mandal* Synthesis of Benzoxazole and Benzothiazole  using  Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino) acetate (o-NosylOXY) both Solution and Solid Phase, 20th CRSI National Symposium in Chemistry, Department of Chemistry, 3rd Feb 2017, Gauhati University, Page 143 (PP-141).

35. Tapasi Kalita, Dharm Dev and Bhubaneswar Mandal* Synthesis of Benzoxazole and Benzothiazole from Carboxylic Acids by Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloximino) acetate and para-Toluenesulfonic Acid, Frontiers in Chemical Sciences 2016, 8th December 2016, Department of Chemistry, IIT Guwahati, Page 124 (P-69).

34. Srinivasa Rao Manne and Bhubaneswar Mandal* Synthesis of Peptide Hydroxamic Acids Directly From Carboxylic Acid using Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma), Frontiers in Chemical Sciences 2016, 8th December 2016, Department of Chemistry, IIT Guwahati, Page 106 (P-51).

33. Rajat Subhra Giri and Bhubaneswar Mandal* On resin Lewis Acid based Peptide Modification on Asp or Glu, Frontiers in Chemical Sciences 2016, 8th December 2016, Department of Chemistry, IIT Guwahati, Page 97 (P-42).

32. Dharm Dev, Jyoti Chandra, and Bhubaneswar Mandal*, Benzoxazole and Benzothiazole Synthesis from Amino Acid in Solution and On resin by Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino) acetate and para-Toluenesulfonic Acid, Frontiers in Chemical Sciences 2016, 8th December 2016, Department of Chemistry, IIT Guwahati, Page 75 (P-20).

31. Sourav Kalita, Ashim Paul, Sujan Kalita, and  Bhubaneswar Mandal, Anti-Diabetic Activity of Aminobenzoic Acid Containing a/b and a/g but not a/d Hybride Peptide, Frontiers in Chemical Sciences 2016, 8th December 2016, Department of Chemistry, IIT Guwahati, Page 50 (OP-13).

30. Srinivasa Rao Manne and Bhubaneswar Mandal* Peptide Hydroxamic Acids synthesis from Carboxylic Acid using Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma), 19th CRSI National Symposium in Chemistry, 14th July 2016, Department of Chemistry, University of North Bengal, (PP45).

29. Tanmay Mondal, Asim Paul, Krishna Chaitanya Nadimpally, and Bhubaneswar Mandal*Aspartimide Formation as a Novel  b-Sheet Breaking Strategy against Alzheimer's Disease, International Conference on Nascent Developments in Chemical Sciences: Opportunities for Academia-Industry Collaboration, 16th October 2015, Department of Chemistry, Birla Institute of Technology and Science, Pilani; Page-335 (PP-256).

28. Srinivasa Rao Manne, Kishore Thalluri, and Bhubaneswar Mandal* Ethyl 2-Cyano-2-(4-nitrophenylsulfonyloxyimino) acetate (4-NBsOXY) as Reagent for Racemization Free Hydroxamic Acids and Ureas Synthesis from Acids, International Conference on Nascent Developments in Chemical Sciences: Opportunities for Academia-Industry Collaboration, 16th October 2015, Department of Chemistry, Birla Institute of Technology and Science, Pilani; Page-316 (PP-237).

27. Bhubaneswar Mandal, Peptide based pro-drug design against Alzheimer's disease, 5th Indian Peptide Symposium - 2015, 24-25 September, JNCASR, Bangalore. Invited lecture, Abstract Book, page 11 (L-9)

26. Dharm Dev, Nani Babu Palakurthy, and Bhubaneswar Mandal*, Synthesis of O-Benzyl Hydroxamates from Carboxylic Acids by using the N-Hydroxy Benzotriazole Esters of Sulfonic Acids, ChemConvene-2015, 8th April, 2015, Department of Chemistry, IIT Guwahati (P-10).

25. Srinivasa Rao Manne, Kishore Thalluri, Rajat Subhra Giri and Bhubaneswar Mandal*, Microwave assisted Chemoselective and Stereoselective Synthesis of Peptide Alcohols from Amides via Transamidation, ChemConvene-2015, 8th April, 2015, Department of Chemistry, IIT Guwahati (P-29).

24. Tanmay Mondal, Ashim Paul and Dr. Bhubaneswar Mandal, A Novel β-Sheet Breaker Strategy Against Amyloid Aggregation and Fibrillogenesis, ChemConvene-2015, 8th April, 2015, Department of Chemistry, IIT Guwahati (P-34).

23. Dharm Dev, and Bhubaneswar Mandal, Ethyl 2-Cyano-2-(2-Nitrobenzene sulfonyloxyimino) Acetate (o-NosylOXY): One of the Best Coupling Reagent at Present, Research Conclave 1st edition, 25th March, 2015, Department of Chemistry, IIT Guwahati (OP-03).

22. Ashim Paul, Tanmay Mondal,  and Bhubaneswar Mandal*, Disruption of toxic Alzheimer's amyloid aggregates into non toxic species by conformationally restricted α/β hybrid peptide. Abstract book: 10th International Symposium on Bio-Organic Chemistry (ISBOC 10), 11th-15th January, 2015, IISER Pune, India with sponsorship of IUPAC, P-088, page 237. (Poster presentation)

21.    Ashim Paul, Dr. Krishna Chaitanya Nadimpally, Tanmay Mondal, Sourav Kalita, and Bhubaneswar Mandal*, Novel Strategies for Peptide Based Drug Design against Alzheimer’s Disease, 13th Eurasia Conference on Chemical Sciences  (EuAsC2S-13), 14th-18th December, 2014, IISc, Bangalore. (Invited lecture in Chemistry of Living Systems Section, CLS-IL-4), Program Book page 40.

20.    Krishna Chaitanya Nadimpally, Ashim Paul, Tanmay mondal, Sourav Kalita and Bhubaneswar Mandal*, Pro-drug concept for anti-alzheimer’s drug design, Abstract book, Frontier in Chemical Sciences (FICS-2014), 4th-6th December, 2014, IIT Guwahati, India, IL-6, Page 12. (Invited lecture)

19.    Ashim Paul, Kishore Thalluri, Srinivasa Rao Manne, Sourav Kalita and Bhubaneswar Mandal*, Synthesis of biologically active peptide alcohols from C-terminal amide under microwave irradiation, Abstract book, Frontier in Chemical Sciences (FICS-2014), 4th-6th December, 2014, IIT Guwahati, India, P-24, Page 70. (Poster presentation)

18.    Dharm Dev, Jyoti Chandra and Bhubaneswar Mandal*, Application of ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino) acetate (o-NosylOXY): amide and peptide synthesis, Abstract book, Frontier in Chemical Sciences (FICS-2014), 4th-6th December, 2014, IIT Guwahati, India, P-8, Page 54. (Poster presentation)

17.    Jyoti Chandra, Dharm Dev and Bhubaneswar Mandal*, Ethyl-2-cyano-2-(2-nitrobenzenesulfonyloxyimino) acetate (2-NBsOXY): a recyclable coupling reagent for synthesis of hydroxamate under mild condition, Abstract book, Frontier in Chemical Sciences (FICS-2014), 4th-6th December, 2014, IIT Guwahati, India, P-39, Page 86. (Poster presentation)

16.    Kishore Thalluri, Dharm Dev, Nani Babu Palakurthy, Srinivasa Rao Manne, Jyoti Chandra and Bhubaneswar Mandal*, The coupling reagents the world in need indeed, Souvenir of international conference on new dimensions in chemistry and chemical technologies ‒ applications in pharma industry, NDCT-2014, under TEQIP-11, JNTU Hyderabad, 23th-25th June, 2014, CHO-06, page 28.


15.    Dharm Dev, Jyoti Chandra, Ashim Paul and
Bhubaneswar Mandal*, Racemization free Esterification Promoted by Ethyl 2-cyano-2-(2-nitrobenzene sulfonyloxyimino) acetate (2-NBsOXY) under milder conditions, 8th Mid-Year chemical research society of India (CRSI), National symposium in chemistry, 10th-12th July, 2014, P-82857, page-130.


14.    Ashim Paul, Tanmay Mondal, Dharm Dev and
Bhubaneswar Mandal*, Inhibition of alzheimer’s amyloid β derived peptide aggregation by β-sheet breaker hybrid peptide, 8th Mid-Year chemical research society of India (CRSI), National symposium in chemistry, 10th-12th July, 2014, P-88429, page-138.

13. Kishore Thalluri and Bhubaneswar Mandal*, Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-Cyanoacetate (Boc-Oxyma) as Coupling Reagent for Racemization free Peptide Synthesis , Abstract Book, 20th ISCB International Conference (ISCBC-2014), 1st-4th March 1-4, University of Delhi, Delhi, India, (poster)P 114, page: 204.

12.    Nani Babu Palakurthy, Dharm Dev and Bhubaneswar Mandal*, Sulfonate esters as useful synthetic reagents, Abstract Book, 1st Annual International Conference (AIC-1) & Industry – CCRS Congress (ICC) 2013, Sanketika Vidya Parishad Engineering College, Visakhapatnam, July 13-14, 2013 (poster).

11.    Krishna Chaitanya Nadimpally,  Ashim Paul, and Bhubaneswar Mandal*,  Towards the development of the concept of β-breaker di-peptides: A proof of principle, Abstract book, 4th Indian Peptide Symposium, 21-22 February, 2013, Saha Institute of Nuclear Physics, Kolkata. S6, page: 31-32 (oral presentation); P32 , page: 140 (poster).

10.  Krishna Chaitanya Nadimpally, Ashim Paul and Bhubaneswar Mandal*, Modulation of aggregation propensity of amyloid beta (1-38) by site specific multiple proline substitution", Abstract Book 8th J-NOST (National Organic Symposium Trust) Conference, 15th – 17th December,2012, IITGuwahati, P 56, page 116.

9.    Bhubaneswar Mandal*; "b-breaker dipeptide: Development of a novel approach for amyloid disruption. Pre-proceeding volume, Young Scientist Research Awardee’s Meet", November 26-28, 2012, BARC, Mumbai. page: 133-135 (oral presentation).

8.    Nani Babu Palakurthy, Dharm Dev, Shubhasmin Rana, Krishna Chaitanya Nadimpally and Bhubaneswar Mandal*; "A facile acid free sulfonamide synthesis under ambient and milder conditions", International symposium on chemistry and chemical biology of natural products (CCBNP-2012), 2nd – 4th August, 2012, IICT Hyderabad. P 173, page: 271.

7.    Dharm Dev, Nani Babu Palakurthy and Bhubaneswar Mandal*; "A faster synthesis of nitriles using sulfonate esters of Oxyma" Abstract Book International symposium on chemistry and chemical biology of natural products (CCBNP-2012), 2nd – 4th August, 2012, IICT Hyderabad. P185, page: 283.

6.  Ashim Paul, Krishna C. Nadimpally, Kishore Thalluri, and Bhubaneswar Mandal*, "One pot protocol for amide synthesis of unprotected amino acids", Abstract book National symposium on recent trends in chemical science and technology (RTCST-2012), 3rd – 4th March, 2012,  IIT Patna, P 28, page 80.

5.  Kishore Thalluri, Krishna C. Nadimpally, Ashim Paul and Bhubaneswar Mandal*, "Reagent economized and waste minimized approach of amide syntheses by one pot", Abstract book National symposium on recent trends in chemical science and technology (RTCST-2012), 3rd – 4th March, 2012,  IIT Patna, P 26, page 78.

4.  Nadimpally Krishna Chaitanya, Kishore Thalluri, Ashim Paul, Nani babu Palakurthy and Bhubaneswar Mandal*; "Catalyst and solvent free amidation of inactive esters of N-protected amino acids: A green chemistry perspective", Abstract Book CRSI-2012 (national symposium), held at IISER Trivandrum & NIIST Trivandrum, 3rd – 5th February, 2012, P 28, Page 68.

3.    Abhijit Saha, N. K. Chaitanya and Bhubaneswar Mandal*; "A rapid repetitive and cost effective chemoselective ligation protocol for peptide Synthesis", Abstract book International Symposium on the advances in Chemical Sciences, IIT Guwahati, 30th January , 2012, P4, page 22.

2.    Nani Babu Palakurthy, Abhijit Saha, Madhusudan Manna and Bhubaneswar Mandal*; “DBU catalyzed Peptide Synthesis from Benzyl esters of Amino acids”, Abstract Book Frontiers in Chemcial Sciences-2010 (national symposium), IIT Guwahati, December 3-4, 2010, P 64, page 93.

1.   Krishna Chaitanya Nadimpally, Kishore Thalluri, Santu Mandal, Bhubaneswar Mandal*; “Facile Synthesis of Water Soluble Peptide Based Polymers” Abstract Book Frontiers in Chemcial Sciences-2010 (national symposium), IIT Guwahati, December 3-4, 2010, P 83, page 113.