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# | Aptamer Name | Aptamer Target (General) | Aptamer Target (Specific) | Length | Affinity | Buffer | GC Content | Sequence | Reference |
---|---|---|---|---|---|---|---|---|---|
131 | von Willebrand Factor (VWF R9.14) | Protein | von Willebrand Factor (VWF) | 76 | 12 nM | Selection Buffer E (20mM HEPES (pH 7.4), 50 mM NaCl, 2 mM CaCl2, and 0.1% BSA) | 59.21% | 5'-GGGAGGACGAUGCGGUGGACGAACUGCCCUCAGCUACUUUCAUGUUGCUGACGCACAGACGACUCGCUGAGGAUCC-3' | S Oney, BA Sullenger, et al. (2007) "Antidote-Controlled Platelet Inhibition Targeting von Willebrand Factor with Aptamers." Oligonucleotides, 17:265-274. |
132 | HIV-1 R5 SU Glycoprotein gp120 (B40t77) | Protein | HIV-1 R5 gp120 | 77 | 31 nM | cHBS buffer: 10 mM HEPES, pH 7.4, 150 mM NaCl, 1 mM CaCl 2, 1 mM MgCl2, 2.7 mM KCl | 54.55% | 5'-GGGAGACAAGACUAGACGCUCAAUGUGGGCCACGCCCGAUUUUACGCUUUUACCCGCACGCGAUUGGUUUGUUUCCC-3' | A. K. Dey et. al. Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1. RNA 11:873-884 |
133 | upanap-12 | Protein | Urokinase-type plasminogen activator | 79 | N/A nM | HBS, 2 mM MgCl2, 0.1% BSA, and 0.025% Tween20 | 44.30% | 5'-GGGGCCACCAACGACAUUUGCGACUGUUAUAACCUAACAGCGACGUAAAGAUAGUUGAUAUAAAUAGUGCCCAUGGAUC-3' | Daniel Miotto Dupont, Jeppe Buur Madsen, Roland Karl Hartmann, et al. Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding. RNA 2010 16: 2360-2369 |
134 | Apramycin (LGA11) | Small Organic | Apramycin and other aminolycosides (AMGs) | 79 | 28.4 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
135 | Apramycin (LS13) | Protein | Apramycin and other aminolycosides (AMGs) | 79 | 35.9 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
136 | Gentamicin (LGA11) | Small Organic | Gentamicin and other Aminoglycosides (AMGs) | 79 | 22.3 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
137 | Kanamycin (LGA11) | Small Organic | Kanamycin and other aminoglycosides (AMGs) | 79 | 52.8 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
138 | Paromomycin (LGA11) | Small Organic | Paromomycin and other Aminoglycosides (AMGs) | 79 | 21.4 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602 |
139 | Streptomycin (LGA11) | Small Organic | Streptomycin and other Aminoglycosides (AMGs) | 79 | 49.9 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
140 | Tobramycin (LGA11) | Small Organic | Tobramycin and other Aminoglycosides (AMGs) | 79 | 19.2 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3’ | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |