# Aptamer Name Aptamer Target (General) Aptamer Target (Specific) Length Affinity Buffer GC Content Sequence Reference
211 Brain-homing peptide (PEPC7) Tissue Murine Brain 9 N/A nM Selection and in vivo imaging performed in mice. 5'-CTSTSAPYC-3' Jingwei, L. Identification of peptide sequences that target to the brain using in vivo phage display. Amino Acids, 2012(42), 2373-2381. doi: 10.1007/s00726-011-0979-y
212 Tumor-derived endothelial cells (PepMW3) Cells Tumor-derived endothelial cells (TDECs) 9 N/A nM IMC Medium: 1X M9 Salts (40 mM Na2HPO4, 20 mM KH2PO4, 8.5 mM NaCl, 20 mM NH4Cl, pH 7.4), 0.2% casamino acids, 0.5% glucose, 1 mM MgCl2.  5'-CGGRRLGGC-3' C K Brown et al. A novel approach for the identificaiton of unique tumor vasculature binding peptides using an E. coli peptide display library. Ann Surg Oncol. 7(2000): 743-749.
213 Alpha V Beta 5 Integrin Cells Alpha V Beta 5 Integrin 9 N/A nM Binding Buffer (50uL PBS/1.5% BSA) NH2-VVISYSMPD-COOCOOH Cardo-Vila et al. "Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V." Molecular Cell, 11(2003): 1151-1162
214 Gelatinase (MMP-9) Protein Matrix Metalloproteinase-9 (MMP-9) 10 N/A nM Incubated overnight at 4 ° C in binding buffer (50 mM TBS buffer (Tris-HCl/0.1 M NaCl, pH 7.5) containing 1% BSA). NH2-CTTHWGFTLC-COOCOOH Koivunen et al. "Tumor targeting with a selective gelatinase inhibitor." Nature Biotechnology, 17(1999): 768 - 774.
215 Peritoneal tumors of gastric cancer Tissue Peritoneal tumors of gastric cancer 10 N/A nM In vivo in mice. Washed with PBS containing 0.5% Tween-20 sorbitan monolaurate. NH2-KLPSWKLPPS-COOCOOH Akita et al. "Identification of oligopeptides binding to peritoneal tumors of gastric cancer." Japanese Cancer Association, 97(2006): 1075-1081.
216 MT1-MMP (swiggle) Protein Membrane-type 1 matrix metalloptroteinase (MT1-MMP) 10 N/A nM  N/A 5'-GGLIPCYFMH-3' Wrickramasinghe, R. D. et al. "Peptide Aptamers as New Tools to Modulate Clathrin-Mediated Internalisation--Inhibition of MT1-MMP Internalisation." BMC Cell Ciology, 11 (2012): 1-15
217 Tumor-derived endothelial cells (tRRL)  Cells Tumor-derived endothelial cells (TDECs) 10 N/A nM  PBS was used for Flow Cytometry assays.  5'-YCGGRRLGGC-3' X Lu et al. Use of radioiodinated peptide arg-arg-leu targeted to neovascualrization as well as tumor cells in molecular tumor imaging. Chin J Cancer Res 24(2012): 52-59.
218 Endothelial Cells (P36) Cells Endothelial Cells 12 2.2 nM Binding Buffer (1 mM glucose, 1% BSA, 10 mM MgSO4) Selection Buffer (0.1% BSA, 1 mM CaCl2, and 10 mM MgCl2) NH2-SQRWTALWQWIG-COOCOOH Herrmann et al. "Selection of cell specific peptides in a rat carotid injury model using a random peptide-presenting bacterial library." Bichemica et Biophysica Acta, 1472(1999): 529-536.
219 Bevacizumab-Responsive Peptide (BRP) Tissue Bevacizumab-treated Tumor 12 N/A nM NH2-LLADTTHHRPWT-COOCOOH Cao et al. "Phage display peptide probes for imaging early response to bevacizumab treatment." Amino Acids, 41(2011): 1103-1112.
220 EphA2 Receptor (YSA peptide)  Tissue EphA2 Receptor 12 186 nM Blocked with 0.5% BSA in TBS and washed with binding buffer (TBS, 1 mM CaCl2, 0.1% Tween 20). NH2-YSAYPDSVPMMS-COOCOOH Koolpe et al. "An Ephrin Mimetic Peptide That Selectively Targets the EphA2 Receptor." J. Biol. Chem., 49(2002): 46974 ƒ??4697.