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# | Aptamer Name | Aptamer Target (General) | Aptamer Target (Specific) | Length | Affinity | Buffer | GC Content | Sequence | Reference |
---|---|---|---|---|---|---|---|---|---|
341 | NADH (ID# 280) | Small Organic | NADH | 49 | 37 nM | Selection Buffer (20 mM HEPES (pH 7.5), 300 mM KC1, and 5 mM MgC12) at room temperature. | 59.18% | 5' GGAACCCAACUAGGCGUUUGAGGGGAUUCGGCCACGGUAACAACCCCUC 3' | Lauhon and Szostak. "RNA Aptamers That Bind Flavin and Nicotinamide Redox Cofactors." Journal of the American Chemical Society, 117(1994): 1246-1257. |
342 | NAD (ID# 151) | Small Organic | NAD | 49 | 2.5 nM | Selection Buffer (20 mM HEPES (pH 7.5), 300 mM KC1, and 5 mM MgC12) at room temperature | 59.18% | 5' GGAACCCAACUAGGCGUUUGAGGGGAUUCGGCCACGGUAACAACCCCUC 3' | Lauhon and Szostak. "RNA Aptamers That Bind Flavin and Nicotinamide Redox Cofactors." Journal of the American Chemical Society, 117(1994): 1246-1257. |
343 | Chloramphenicol (Cm1) | Small Organic | Chloramphenicol | 50 | 110 nM | Binding Buffer (20 mM MgCl2, 400 mM NaCl, 100 mM bis-Tris (pH 6.4) | 42.00% | 5' GGGAUCACAGUGAAAAAAGACGUGUGAAUGUCACACUGAAAAAAGAUCCC 3' | Burke et al. "RNA aptamers to the peptidyl transferase inhibitor chloramphenicol." Chemistry & Biology, 4(1997): 833-843. |
344 | Periostin Aptamer (PNDA-3) | Protein | Periostin | 51 | 1.07 nM | 40 mM/1 HEPES, 102 mM/1 NaCl, 5 mM/1mol/1g Cl2,5 mM KCl | 52.94% | Lee, Y., Kim, I., Park, S., Kim, Y., Wu, S., Lee, J., Noh, D., Kim, K., Ryu, S. and Suh, P. "Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis." The American Society of Gene & Cell Therapy 21.5 (2013): 1004-13. | |
345 | A15 (ID# 564) | Other | Penetrating the Blood Brain Barrier | Not 54, 202 according to dB | 10mM HEPES, pH 7.4, 50mM NaCl, 1mM MgCl2, 1mM CaCl2, 0.01% BSA | 77.78% | Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell Therapy | ||
346 | A14 (ID# 566) | Other | Penetrating the Blood Brain Barrier (BBB) | 180 | NA | 10mM HEPES, pH 7.4, 50mM NaCl, 1mM MgCl2, 1mM CaCl2, 0.01% BSA | 78.18% | Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell Therapy | |
347 | A09 (ID# 568) | Other | Penetrating the Blood Brain Barrier | 55 | 10mM HEPES, pH 7.4, 50mM NaCl, 1mM MgCl2, 1mM CaCl2, 0.01% BSA | 78.18% | Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell Therapy | ||
348 | Adenosine Triphosphate (1-1MIN) | Small Organic | Adenosine Triphosphate / ATP | 57 | 4.8 µM | 300 mM NaCl, 10 mM MgCl2 OR 30 mM MgCl2, 0.1 mM EDTA, and 25 mM Tris (pH 7.8) | 54.39% | 5' GGGAGAUCUACGGAUCUCAGGGCUCUUACGGGAGCUACAUGGAAGGAGUCCAUGUGU 3' | P Sazani, R Larralde, and J Szostak.(2004) "A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP." J Am Chem Soc. 126: 8370-8371. |
349 | Dopamine (dopa1.30/c.30) (ID# 402) | Small Organic | Dopamine | 58 | NA | Column Buffer: 50 mM Tris-HCl (pH 7.4), 5 mM MgCl2, and 0.5 M or 0.15 M NaCl | 60.34% | 5' GUCUCUGUGUGCGCCAGAGAACACUGGGGCAGAUAUGGGCCACACAGAAUGAGGCCC 3' | Mannironi, C., et al. "In Vitro Selection of Dopamine RNA Ligands." Biochemistry, 36 (1997): 9726-9734. |
350 | AMPA GluR2 (AN58) (ID# 444) | Protein | AMPA GluR2 Glutamate Receptor Channel | 58 | 419 pM | 10% DMSO in Extracellular Buffer: 150 mM NaCl, 3 mM KCl, 1 mM CaCl2, 1 MgCl2, 10 HEPEs (pH 7.4) | 50.00% | 5' GGGCGAAUUCAACUGCCAUCUAGGCAGUAACCAGGAGUUAGUAGGACAAGUUUCGUCC 3' | Z. Huang et al. RNA aptamers selected against the GluR2 glutamate receptor channel. Biochemistry 46(2007): 12648 - 12655. |