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# | Aptamer Name | Aptamer Target (General) | Aptamer Target (Specific) | Length | Affinity | Buffer | GC Content | Sequence | Reference |
---|---|---|---|---|---|---|---|---|---|
141 | Gentamycin (LS13) | Small Organic | Gentamycin and other Aminoglycosides (AMGs) | 79 | 26.7 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
142 | Neomycin (LGA11) | Small Organic | Neomycin and other aminogycosides (AMGs) | 79 | 40.3 nM | Binding Buffer: PBS with 10% (v/v) methanol | 56.96% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
143 | Kanamycin (LS13) | Small Organic | Kanamycin and other Aminoglycosides (AMGs) | 79 | 69.9 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
144 | Neomycin (LS13) | Small Organic | Neomycin and other Aminoglycosides (AMGs) | 79 | 37.0 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602 |
145 | Paromomycin (LS11) | Small Organic | Paromomycin and other Aminoglycosides (AMGs) | 79 | 19.8 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602 |
146 | Streptomycin (LS11) | Small Organic | Streptomycin and other Aminoglycosides (AMGs) | 79 | 19.8 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602. |
147 | Tobramycin | Small Organic | Tobramycin and other Aminoglycosides (AMGs) | 79 | 24.8 nM | Binding Buffer: PBS with 10% (v/v) methanol | 46.84% | 5'-GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC-3' | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. Anal. Chem. (2012) 84: 6595-6602 |
148 | Plasminogen Activator Inhibitor-1 (paionap-5) | Protein | Plasminogen Activator Inhibitor-1 | 79 | 1.58 nM | HBS buffer (pH 7.4), 2mM MgCl2, 0.05% Tween 20. | 50.63% | 5'-GGGGCCACCAACGACAUUGAACCACGUAGGCUCGUUUCUGAGCCGAUCUCGAUGUUGAUAUAAAUAGUGCCCAUGGAUC-3' | Madsen, J.B., et al. "RNA Aptamers as Conformational Probes and Regulatory Agents for Plasminogen Activator Inhibitor-1." Biochemistry, 49, (2010), 4103-4115. |
149 | Plasminogen Activator Inhibitor-1 (paionap-40) | Protein | Plasminogen Activator Inhibitor-1 | 79 | 1.23 nM | HBS buffer (pH 7.4), 2mM MgCl2, 0.05% Tween 20. | 45.57% | 5'-GGGGCCACCAACGACAUUUAUCGAAUUGAUAACCUUACGCGAGAGCGUAGUUCGUUGAUAUAAAUAGUGCCCAUGGAUC-3' | Madsen, J.B., et al. "RNA Aptamers as Conformational Probes and Regulatory Agents for Plasminogen Activator Inhibitor-1." Biochemistry, 49, (2010), 4103-4115. |
150 | OX40 (Aptamer 9.8) | Protein | Murine OX40 (a tumor necrosis factor (TNF) receptor on the surface of T Cells) | 80 | 8 nM | Binding Buffer: 150 mM NaCl, 2 mM CaCl2, and 20 mM Hepes (pH 7.4) | 58.75% | 5'-GGGAGGACGAUGCGGCAGUCUGCAUCGUAGGAAUCGCCACCGUAUACUUUCCCACCAGACGACUCGCUGAGGAUCCGAGA-3' | C M Dollins et al. Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. Chem Biol. 15(2008):675-682. |