# Aptamer Name Aptamer Target (General) Aptamer Target (Specific) Length Affinity Buffer GC Content Sequence Reference
191 Human Umbilical Vein Endothelial Cells Cells Human Umbilical Vein Endothelial Cells 5 N/A nM N/A NH2-CGKRK-COOCOOH Agemy et al. "Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma." PNAS, doi: 10.1073/pnas.1114518108.
192 Trypsin Protein Trypsin 6 N/A pM 89% Inhibition Buffer (0.1M Tris-HCl, 0.025M CaCl2 (pH 7.8)) NH2-TTKIFT-COOCOOH Yokobayashi et al. "Directed evolution of trypsin inhibiting peptides using a genetic algorithm." Journal of the Chemical Society, 1(1996): 2435-2437
193 Liver-Specific Ligands (236) Tissue Liver-Specific Ligands 7 n/a nM Selection Buffer (PBS, 1 M NaCl, and 2% Triton X-100) Wash Buffers (0.1% Sodium Borohydride, 0.1 M Phosphate Buffer) (PBS, 5% BSA, 0.1% cold water fish gelatin, and 5% normal goat serum in PBS) Incubation Buffer (PBS and 1.1% BSA-C) NH2-QRVLVKK-COOCOOH Ludtke et al. "In Vivo Selection and Validation of Liver-Specific Ligands Using a New T7 Phage Peptide Display System." Drug Delivery, 14(2007): 357-369.
194 Renal Tissue (Glomerulus and Intertubular tissue) Tissue Glomerular vessels and renal intertubular tissue 7 N/A nM In vivo mice. NH2-CLPVASC-COOCOOH Pasqualini and Ruoslahti. "Organ targeting in vivo using phage display peptide libraries." Letters to Nature, 380(1996):364-366.
195 VEGF-KDR Tissue VEGF-KDR 7 ~80 µM Binding Buffer: DMEM supplemented with 20 mM HEPES (pH 7.4) and 2 mg/mL gelatin NH2-ATWLPPR-COOCOOH Binetruy-Tournaire et al. "Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis." The EMBO Journal, 19(2000): 1525-1533
196 Mouse Placenta Tissue Neonatal Fc Receptor 7 N/A nM In vivo in pregnant mice. NH2-TPKTSVT-COOCOOH Kolonin et al. "Teratogenicity induced by targeting a placental immunoglobulin transporter." PNAS, 99(2002): 13055-13060.
197 Nestin Protein expressed in Brain Tumors (clone 17) Protein Nestin Protein expressed in Brain Tumors 7 N/A nM Binding Buffer (PBS containing 1% BSA) Wash Buffer (PBS with 0.05% Tween 20), 4°C NH2-AQTLAPS-COOCOOH Beck et al. "Indentification of a peptide that interacts with Nestin protein expressed in brain cancer cells." Biomaterials, 32(2011): 8518-8528
198 ErbB2 Tyrosine Kinase Receptor (Ph7-2) Protein ErbB2 Tyrosine Kinase Receptor 7 N/A nM N/A 5'-LTVSPWY-3' Shadidi and Sioud. "Identification of Novel Peptides for the Specific Delivery of Therapeutics into Cancer Cells." The FASEB Journal, 2, (2003): 256-8.
199 Human Transferrin Receptor (T7) Protein Human Transferrin Receptor (hTfR) 7 N/A nM Serum-free Opti-MEM. 5'-HAIYPRH-3' J. H. Lee et al. Receptor mediated uptake of peptides that bind the human transferrin receptor. Eur. J. Biochm. 268(2001): 2004-2012.
200 VEGF-Stimulated HUVECs Tissue VEGF-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) 8 N/A nM In vivo mice. NH2-PVVLFPLH-COOCOOH Asai et al. "Isolation of a Novel Peptide Homing to Tumor-Derived Neovasculature That Suppresses Tumor Growth." Biological Pharmaceutical Bulletin, 25(2002): 904-906.